Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.
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Follicle-stimulating hormone (FSH) activates extracellular signal-regulated kinase phosphorylation independently of beta-arrestin- and dynamin-mediated FSH receptor internalizationbeta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2Gravin-mediated formation of signaling complexes in beta 2-adrenergic receptor desensitization and resensitizationEarly endosomal regulation of Smad-dependent signaling in endothelial cellsHeterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathwayPhospholipase D: molecular and cell biology of a novel gene familyEndocytosis, actin cytoskeleton, and signalingThe endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brainHsc/Hsp70 interacting protein (hip) associates with CXCR2 and regulates the receptor signaling and traffickingBeta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transductionThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsLigand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosisHeterotrimeric G protein subunits are located on rat liver endosomesThe mechanism of μ-opioid receptor (MOR)-TRPV1 crosstalk in TRPV1 activation involves morphine anti-nociception, tolerance and dependenceActivation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization.Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptorsPhosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinasesThe inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factorGIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activationDynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrateDirect binding of beta-arrestins to two distinct intracellular domains of the delta opioid receptorBeta-arrestins: multifunctional cellular mediatorsCharacterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanismsNicotinic acid receptor agonists differentially activate downstream effectorsActivation of the p38 and p42/p44 mitogen-activated protein kinase families by the histamine H(1) receptor in DDT(1)MF-2 cellsLigand internalization and recycling by human recombinant somatostatin type 4 (h sst(4)) receptors expressed in CHO-K1 cellsTranslation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulationInsulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neuronsSodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal controlEndocytosis and signalling: intertwining molecular networksIntersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis.Gi-mediated tyrosine phosphorylation of Grb2 (growth-factor-receptor-bound protein 2)-bound dynamin-II by lysophosphatidic acidβ-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.Parathyroid hormone-related peptide stimulates osteogenic cell proliferation through protein kinase C activation of the Ras/mitogen-activated protein kinase signaling pathway.Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone.Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases.A critical role for endocytosis in Wnt signaling
P2860
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P2860
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Essential role for G protein-c ...... ogen-activated protein kinase.
@en
type
label
Essential role for G protein-c ...... ogen-activated protein kinase.
@en
prefLabel
Essential role for G protein-c ...... ogen-activated protein kinase.
@en
P2093
P2860
P356
P1476
Essential role for G protein-c ...... togen-activated protein kinase
@en
P2093
G J Della Rocca
R J Lefkowitz
S S Ferguson
P2860
P304
P356
10.1074/JBC.273.2.685
P407
P577
1998-01-01T00:00:00Z