Phosphatidylinositol 3-kinase activity is required for early endosome fusion.
about
Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosomeThe type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membraneHuman VPS34 is required for internal vesicle formation within multivesicular endosomesClass III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane trafficSyntaxin 7, a novel syntaxin member associated with the early endosomal compartmentWortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cellsRegulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase.Role for phosphatidylinositol in nuclear envelope formationHyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1Membrane fusion plays an important role in gene transfection mediated by cationic liposomes.Membrane protein location-dependent regulation by PI3K (III) and rabenosyn-5 in Drosophila wing cells.Regulation of endosome fusion.The cytoplasmic tail of invariant chain regulates endosome fusion and morphologyEnhancement of cell membrane invaginations, vesiculation and uptake of macromolecules by protonation of the cell surface.Mechanism of interferon-gamma-induced increase in T84 intestinal epithelial tight junction.Phosphatidylinositol 4,5-bisphosphate regulates two steps of homotypic vacuole fusionInactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organizationEvidence for apical endocytosis in polarized hepatic cells: phosphoinositide 3-kinase inhibitors lead to the lysosomal accumulation of resident apical plasma membrane proteinsChimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathwaysThe phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting.Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptidesWortmannin induces homotypic fusion of plant prevacuolar compartmentsTethering molecules in membrane traffic.Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro.Phosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network.Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling.Roles of phosphatidylinositol 3-kinase in root hair growth.The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.Inhibition of endosome fusion by wortmannin persists in the presence of activated Rab5.Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase.Pet, a non-AB toxin, is transported and translocated into epithelial cells by a retrograde trafficking pathway.Rice SCAMP1 defines clathrin-coated, trans-golgi-located tubular-vesicular structures as an early endosome in tobacco BY-2 cells.Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3.Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics.Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative.Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin.PIKfyve regulation of endosome-linked pathways.Early events in integrin alphavbeta6-mediated cell entry of foot-and-mouth disease virusPolyphosphoinositide inclusion in artificial lipid bilayer vesicles promotes divalent cation-dependent membrane fusion.The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization.
P2860
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P2860
Phosphatidylinositol 3-kinase activity is required for early endosome fusion.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Phosphatidylinositol 3-kinase activity is required for early endosome fusion.
@en
type
label
Phosphatidylinositol 3-kinase activity is required for early endosome fusion.
@en
prefLabel
Phosphatidylinositol 3-kinase activity is required for early endosome fusion.
@en
P2860
P356
P1433
P1476
Phosphatidylinositol 3-kinase activity is required for early endosome fusion
@en
P2093
M J Clague
P2860
P356
10.1042/BJ3110031
P407
P478
311 ( Pt 1)
P577
1995-10-01T00:00:00Z