Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
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Structural Basis of the CD8 /MHC Class I Interaction: Focused Recognition Orients CD8 to a T Cell Proximal PositionCD3 delta establishes a functional link between the T cell receptor and CD8Differential modulation of CD8beta by rat gammadelta and alphabeta T cells after activationCD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.Immune response during disease and recovery in the elderly.CD8+ T cells mediate recovery and immunopathology in West Nile virus encephalitisRapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.Phenotypic and functional evaluation of CD3+CD4-CD8- T cells in human CD8 immunodeficiency.Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.Familial CD8 deficiency due to a mutation in the CD8 alpha gene.HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells.A constant affinity threshold for T cell tolerance.Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation.Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiationCD8 beta chain influences CD8 alpha chain-associated Lck kinase activity.The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimersCD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity.An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Role of coreceptors in positive selection and lineage commitment.TL and CD8αα: Enigmatic partners in mucosal immunity.Views on helper/cytotoxic lineage choice from a bottom-up approach.Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling.IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cellsReduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.Glu227-->Lys substitution in the acidic loop of major histocompatibility complex class I alpha 3 domain distinguishes low avidity CD8 coreceptor and avidity-enhanced CD8 accessory functions.Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.
P2860
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P2860
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
@en
type
label
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
@en
prefLabel
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
@en
P2093
P356
P1433
P1476
Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.
@en
P2093
Kanagawa O
Nakauchi H
Nakayama K
P304
P356
10.1126/SCIENCE.8108731
P407
P577
1994-02-01T00:00:00Z