CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
about
The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsDifferential modulation of CD8beta by rat gammadelta and alphabeta T cells after activationCD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.Extracellular domains of CD8α and CD8ß subunits are sufficient for HLA class I restricted helper functions of TCR-engineered CD4(+) T cells.CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexesCritical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimersAn opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes.Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen.CD8 lineage commitment in the absence of CD8.IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.Duality of the murine CD8 compartment.Vaccines as early therapeutic interventions for cancer therapy: neutralising the immunosuppressive tumour environment and increasing T cell avidity may lead to improved responses.The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cellsT cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs.Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggeringCharacterization of avian γδ T-cell subsets after Salmonella enterica serovar Typhimurium infection of chicksCD8αα Expression Marks Terminally Differentiated Human CD8+ T Cells Expanded in Chronic Viral Infection.AV.TK-mediated killing of subcutaneous tumors in situ results in effective immunization against established secondary intracranial tumor deposits.CD8beta/CD28 expression defines functionally distinct populations of peripheral blood T lymphocytes.The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities.CD8αβ Has Two Distinct Binding Modes of Interaction with Peptide-Major Histocompatibility Complex Class I2D Kinetic Analysis of TCR and CD8 Coreceptor for LCMV GP33 Epitopes
P2860
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P2860
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@ast
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@en
type
label
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@ast
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@en
prefLabel
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@ast
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@en
P2093
P2860
P356
P1476
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.6.2439
P407
P577
1996-12-01T00:00:00Z