Inhibition of beta-amyloid production by activation of protein kinase C.
about
Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding proteinActivation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrilsSerotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretionAmyloid precursor protein processing is stimulated by metabotropic glutamate receptors.Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activationAlzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts.Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway.Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo.Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.Intranasal therapeutic strategies for management of Alzheimer's disease.Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein.Fleshing out the amyloid cascade hypothesis: the molecular biology of Alzheimer's disease.Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.Metallothionein-III increases ADAM10 activity in association with furin, PC7, and PKCα during non-amyloidogenic processing.Protein Phosphorylation is a Key Mechanism in Alzheimer's Disease.Alzheimer's disease, beta-amyloidosis, and aging.Dorothy Russell Memorial Lecture. The molecular pathology of Alzheimer's disease: are we any closer to understanding the neurodegenerative process?Regulation of APP processing by intra- and intercellular signals.X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion.Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.Amyloid precursor protein secretion and beta A4 amyloid generation are not mutually exclusive.Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C.Constitutive overactivation of protein kinase C in guinea pig brain increases alpha-secretory APP processing without decreasing beta-amyloid generation.Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.Cortico-hippocampal APP and NGF levels are dynamically altered by cholinergic muscarinic antagonist or M1 agonist treatment in normal mice.Modulation of amyloid precursor protein cleavage by cellular sphingolipids.Increased neuronal and glial expression of protein kinase C isoforms in neocortex of transgenic Tg2576 mice with amyloid pathology.Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.Amyloid precursor protein beta-secretase (BACE) mRNA expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines and growth factors.Potential therapeutic targets for Alzheimer’s disease
P2860
Q28138703-F2762881-EAB5-4501-B6F4-4F024AD1AFFAQ28570115-F58A59F1-5C01-4726-AC98-BF07350D424BQ28609364-F31C7853-FF35-426B-A46E-E556EC60011DQ34029499-911751FB-44B9-428D-8A19-27EEB0E43E43Q34549472-D3AC1966-EDAC-4B92-9657-AF9572B7DB93Q35237138-9DE262F2-F8FB-4CD1-B4C3-F99415C5EDAFQ35734048-717D3C92-AA83-4B5C-88D1-D05DD76B4456Q36091651-D7F99D03-4ACD-4907-9522-F1F419BA4D1DQ36173028-E018E954-C56B-4F1D-BCF6-F194083CCCF8Q36610341-6A5BBE6E-3C29-4F6E-B1B0-771F7BC61EAFQ37105896-C262B3FF-4A6E-4769-9A35-92B1E12A772CQ37357625-BAE66FF3-B059-4BED-A843-BD0BD6EF6C90Q38176935-6BCED0D2-067D-4D91-B335-B490A5429EA7Q38362682-505B9B0F-7C50-4817-A599-895862BB136FQ38578250-8BA31F44-0D5A-4D91-B04A-D3DE8C15E157Q38858846-C12254E5-2AE6-4FB3-857F-94D55FE69F0BQ38991860-0DF6AC41-7386-49C6-8D28-0515D75D9481Q39319453-46F9B9CE-F515-4275-87FE-86BBB6B41FD1Q40494272-671635CD-F677-41AD-9249-4054892D74BBQ40561527-91043C3C-97C7-4563-A22F-A18326A5253CQ40983125-C0AEBA9C-6163-47D5-9988-14B97912E0FFQ41014746-5CFD22E5-CD11-4F7A-9BE4-365671D9D083Q41350956-04BD7E09-026D-4B92-A453-10DDDDB6B364Q41450284-E05A461C-369A-4B3A-A1DE-B659D4BE7C2FQ41780891-7338F286-3AC1-482F-97E2-25E132A032EDQ41924331-9A6F7974-46A8-4419-8614-DBA92A1329BFQ42984978-011EDDC7-9540-46D6-8672-CE14E80680E9Q43904357-7AC67D85-AF41-4E37-AD21-49E1A586DFB4Q44722885-06C59CFD-7714-4E9B-A691-2819CDF0E3F3Q49044145-CDE1497D-6893-4C10-BA26-11DCA4AADB68Q53213386-BBF73D2F-1C4F-4C9C-ABCF-8B665E78492DQ53240567-646ECA47-A00D-44FD-9C59-37EE771774A8Q58842921-BDE093B6-A7C1-4E04-AC78-2BC5DF00472C
P2860
Inhibition of beta-amyloid production by activation of protein kinase C.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Inhibition of beta-amyloid production by activation of protein kinase C.
@en
type
label
Inhibition of beta-amyloid production by activation of protein kinase C.
@en
prefLabel
Inhibition of beta-amyloid production by activation of protein kinase C.
@en
P2093
P2860
P1476
Inhibition of beta-amyloid production by activation of protein kinase C.
@en
P2093
Busciglio J
Yankner BA
P2860
P304
P356
10.1111/J.1471-4159.1993.TB07479.X
P407
P577
1993-12-01T00:00:00Z