Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth.
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Diverse forms of a receptor for acidic and basic fibroblast growth factorsA tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1Recent developments in the cell biology of basic fibroblast growth factorThe HIV-1 TAT protein induces the expression and extracellular appearance of acidic fibroblast growth factorGene expression of fibroblast growth factors in human gliomas and meningiomas: demonstration of cellular source of basic fibroblast growth factor mRNA and peptide in tumor tissues.Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells.Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells.Elevated expression of basic fibroblast growth factor in an immortalized rabbit smooth muscle cell lineIn vitro splicing of fibronectin pre-mRNAsTransformation of NIH 3T3 cells with basic fibroblast growth factor or the hst/K-fgf oncogene causes downregulation of the fibroblast growth factor receptor: reversal of morphological transformation and restoration of receptor number by suramin.Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms.Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses.The K-fgf/hst oncogene induces transformation through an autocrine mechanism that requires extracellular stimulation of the mitogenic pathwayMapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis.Biological activities of fibroblast growth factors.Secreted or nonsecreted forms of acidic fibroblast growth factor produced by transfected epithelial cells influence cell morphology, motility, and invasive potential.Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability.Growth factors as transforming proteins.PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death.Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization.Constitutive expression of FGF2/bFGF in non-tumorigenic human prostatic epithelial cells results in the acquisition of a partial neoplastic phenotype.Cells retrovirally transfected with fibroblast growth factor-2 isoforms exhibit altered adenylate cyclase activity and G-protein functionality.Cell transformation by kFGF requires secretion but not glycosylation.Multiple forms of bFGF: differential nuclear and cell surface localization.Production of basic fibroblast growth factor-like factor by cultured human cholangiocellular carcinoma cells.Comparison of the ability of basic and acidic fibroblast growth factor to stimulate the proliferation of an established keratinocyte cell line: modulation of their biological effects by heparin, transforming growth factor beta (TGF beta), and epiderTransformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environmentInhibition of cell growth and tumorigenesis of human glioblastoma cells by a neutralizing antibody against human basic fibroblast growth factor.cDNA cloning of a novel, developmentally regulated immediate early gene activated by fibroblast growth factor and encoding a nuclear protein.Expression of modified bFGF cDNAs in mammalian cells.Translocation of FGF2 to the cell surface without release into conditioned media.Adenoviral-mediated expression of antisense RNA to fibroblast growth factors disrupts murine vascular development.Stromelysin-3 Is Induced in Tumor/Stroma Cocultures and Inactivated via a Tumor-specific and Basic Fibroblast Growth Factor-dependent Mechanism
P2860
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P2860
Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Expression of human basic fibr ...... lts in autonomous cell growth.
@en
type
label
Expression of human basic fibr ...... lts in autonomous cell growth.
@en
prefLabel
Expression of human basic fibr ...... lts in autonomous cell growth.
@en
P2093
P2860
P356
P1476
Expression of human basic fibr ...... lts in autonomous cell growth.
@en
P2093
Gospodarowicz D
Mitchell R
P2860
P304
P356
10.1083/JCB.106.4.1385
P407
P577
1988-04-01T00:00:00Z