Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. - Wikidata - awgldk - TriplyDB

Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation.

Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation.

http://www.wikidata.org/entity/Q41579424

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Cellular Mechanisms of Ciliary Length Control Measuring the primary cilium length: improved method for unbiased high-throughput analysis.A role for the membrane in regulating Chlamydomonas flagellar length.Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells Crystal structure of the intraflagellar transport complex 25/27 Assembling a primary cilium.The Cilium: Cellular Antenna and Central Processing Unit Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex Lack of dopaminergic inputs elongates the primary cilia of striatal neurons Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation.Control of vertebrate intraflagellar transport by the planar cell polarity effector Fuz Transmembrane protein OSTA-1 shapes sensory cilia morphology via regulation of intracellular membrane trafficking in C. elegans.Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle Evolutionary origins of sensation in metazoans: functional evidence for a new sensory organ in sponges Direct evidence for BBSome-associated intraflagellar transport reveals distinct properties of native mammalian cilia.Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium.A chemical screen identifies class a g-protein coupled receptors as regulators of cilia.Orphan G-protein coupled receptor 22 (Gpr22) regulates cilia length and structure in the zebrafish Kupffer's vesicle Detection of copy number variants reveals association of cilia genes with neural tube defects.Development of a method for the measurement of primary cilia length in 3D.Soluble levels of cytosolic tubulin regulate ciliary length control The phosphorylation state of an aurora-like kinase marks the length of growing flagella in Chlamydomonas Controlling fertilization and cAMP signaling in sperm by optogenetics.Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling Cilia and cell cycle re-entry: more than a coincidence.Subcellular size.Stages of ciliogenesis and regulation of ciliary length Flow stimulated endocytosis in the proximal tubule.Identification of drugs that restore primary cilium expression in cancer cells.Genetic Ablation of Type III Adenylyl Cyclase Exerts Region-Specific Effects on Cilia Architecture in the Mouse Nose.

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P2860

Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation.

http://www.wikidata.org/entity/Q41579424

description

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Identification of signaling pa ...... and flow-mediated adaptation.

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Identification of signaling pa ...... and flow-mediated adaptation.

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Identification of signaling pa ...... and flow-mediated adaptation.

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J.CUB.2009.11.072

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Current Biology

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Identification of signaling pa ...... and flow-mediated adaptation.

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Bjorn R Olsen

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Elona Kolpakova-Hart

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Jagesh V Shah

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Jing Zhou

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Tatiana Y Besschetnova

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Yinghua Guan

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P2860

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

A motility in the eukaryotic flagellum unrelated to flagellar beating

Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors.

Microtubule acetylation promotes kinesin-1 binding and transport.

Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

The vertebrate primary cilium in development, homeostasis, and disease

Overview of structure and function of mammalian cilia

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10.1016/J.CUB.2009.11.072

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20096584

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2990526

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