c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. - Wikidata - awgldk - TriplyDB

c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice.

c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice.

http://www.wikidata.org/entity/Q41589752

about

Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective Cancer Stem Cell Hierarchy in Glioblastoma Multiforme An integrative view on sex differences in brain tumors A review of the past, present, and future directions of neoplasia Coming of Age in the Life of Signaling pathways in medulloblastoma.Brain tumor stem cells.Oncogene interactions are required for glioma development and progression as revealed by a tissue specific transgenic mouse model Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms.Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.Immunohistochemical analysis of SOX6 expression in human brain tumors.Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma.Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.Clonal selection drives genetic divergence of metastatic medulloblastoma.Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.Development of a murine model for blastoid variant mantle-cell lymphoma Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma Medulloblastoma: molecular genetics and animal models.DNA-microarray analysis of brain cancer: molecular classification for therapy.Developmental neurobiology and the origin of brain tumors.HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells Morphing into cancer: the role of developmental signaling pathways in brain tumor formation.Functional genomics identifies drivers of medulloblastoma dissemination.Review: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions.PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo.Medulloblastoma: therapy and biologic considerations.Targeting stem cells in brain tumors.The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours?Chloride accumulation drives volume dynamics underlying cell proliferation and migration.Genetically engineered mouse models of brain cancer and the promise of preclinical testing Only in congenial soil: the microenvironment in brain tumorigenesis.A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity.SHH pathway and cerebellar development.

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c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice.

http://www.wikidata.org/entity/Q41589752

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Carolyn A Pedone

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Cheryl M Coffin

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Daniel W Fults

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Eric C Holland

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Ganesh Rao

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P2860

Activating Smoothened mutations in sporadic basal-cell carcinoma

The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival

Proteolytic processing yields two secreted forms of sonic hedgehog

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

Sonic hedgehog regulates the growth and patterning of the cerebellum

NeuN, a neuronal specific nuclear protein in vertebrates

CNS stem cells express a new class of intermediate filament protein

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

Altered neural cell fates and medulloblastoma in mouse patched mutants

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