about
Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transferCommon structural basis for constitutive activity of the ghrelin receptor familyConstitutive neuropeptide Y Y(4) receptor expression in human colonic adenocarcinoma cell linesFluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptorsUnravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data.Dimerization of ABCG2 analysed by bimolecular fluorescence complementation.Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networksA functional comparison of recombinant and native somatostatin sst2 receptor variants in epithelia.Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor.Dissecting the pharmacology of G protein-coupled receptor signaling complexes using bimolecular fluorescence complementation.Plasma membrane dynamics and tetrameric organisation of ABCG2 transporters in mammalian cells revealed by single particle imaging techniques.Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119.Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1Quantitative analysis of neuropeptide Y receptor association with beta-arrestin2 measured by bimolecular fluorescence complementation.Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor.Role of the C terminus in neuropeptide Y Y1 receptor desensitization and internalization.Modulation of chloride, potassium and bicarbonate transport by muscarinic receptors in a human adenocarcinoma cell line.Inhibition of cyclic AMP-dependent chloride secretion by PP receptors and alpha 2-adrenoceptors in a human colonic epithelial cell line.Biased Gs versus Gq proteins and β-arrestin signaling in the NK1 receptor determined by interactions in the water hydrogen bond networkDeciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis.Control of signalling efficacy by palmitoylation of the rat Y1 receptor.Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors.Differential signaling by splice variants of the human free fatty acid receptor GPR120.Unique interaction pattern for a functionally biased ghrelin receptor agonist.Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids.The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor.Y(4) receptors mediate the inhibitory responses of pancreatic polypeptide in human and mouse colon mucosa.The Peptide PnPP-19, a Spider Toxin Derivative, Activates μ-Opioid Receptors and Modulates Calcium Channels.Synthetic routes to the Neuropeptide Y Y1 receptor antagonist 1229U91 and related analogues for SAR studies and cell-based imaging.Identification of a Cyanine-Dye Labeled Peptidic Ligand for Y1R and Y4R, Based upon the Neuropeptide Y C-Terminal Analogue, BVD-15.Optically Pure, Structural, and Fluorescent Analogues of a Dimeric Y4 Receptor Agonist Derived by an Olefin Metathesis Approach.A G protein-coupled receptor dimer imaging assay reveals selectively modified pharmacology of neuropeptide Y Y1/Y5 receptor heterodimersApplication of fluorescence correlation spectroscopy to study substrate binding in styrene maleic acid lipid copolymer encapsulated ABCG2The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complexRed-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M2 ReceptorFluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Nicholas D. Holliday
@ast
Nicholas D. Holliday
@en
Nicholas D. Holliday
@es
Nicholas D. Holliday
@sl
type
label
Nicholas D. Holliday
@ast
Nicholas D. Holliday
@en
Nicholas D. Holliday
@es
Nicholas D. Holliday
@sl
prefLabel
Nicholas D. Holliday
@ast
Nicholas D. Holliday
@en
Nicholas D. Holliday
@es
Nicholas D. Holliday
@sl
P106
P1153
7004174500
P21
P31
P496
0000-0002-2900-828X