ADI, autophagy and apoptosis: metabolic stress as a therapeutic option for prostate cancer.
about
Arginine Metabolism in Bacterial Pathogenesis and Cancer TherapyRole of autophagy in suppression of inflammation and cancer.Arginine deiminase expressed in vivo, driven by human telomerase reverse transcriptase promoter, displays high hepatoma targeting and oncolytic efficiency.A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients.Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy.Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft modelArginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells.A long noncoding RNA connects c-Myc to tumor metabolism.Bioengineered human arginase I with enhanced activity and stability controls hepatocellular and pancreatic carcinoma xenografts.Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteinsAutophagy as a modulator and target in prostate cancer.Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells.Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetaseEnhanced autophagy in cytarabine arabinoside-resistant U937 leukemia cells and its potential as a target for overcoming resistance.Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma.Targeting autophagy during cancer therapy to improve clinical outcomes.Modulating autophagy: a strategy for cancer therapyTargeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges.Targeting asparagine and autophagy for pulmonary adenocarcinoma therapy.Arginine dependence of tumor cells: targeting a chink in cancer's armor.Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancerBioengineered arginase I increases caspase-3 expression of hepatocellular and pancreatic carcinoma cells despite induction of argininosuccinate synthetase-1.Negative LC3b immunoreactivity in cancer cells is an independent prognostic predictor of prostate cancer specific death.Autophagy suppression potentiates the anti-glioblastoma effect of asparaginase in vitro and in vivo.
P2860
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P2860
ADI, autophagy and apoptosis: metabolic stress as a therapeutic option for prostate cancer.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
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2009年论文
@zh-cn
name
ADI, autophagy and apoptosis: ...... ic option for prostate cancer.
@en
type
label
ADI, autophagy and apoptosis: ...... ic option for prostate cancer.
@en
prefLabel
ADI, autophagy and apoptosis: ...... ic option for prostate cancer.
@en
P356
P1433
P1476
ADI, autophagy and apoptosis: ...... ic option for prostate cancer.
@en
P2093
Hsing-Jien Kung
Richard J Bold
P304
P356
10.4161/AUTO.5.4.8252
P50
P577
2009-05-20T00:00:00Z