A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia.
about
Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the BrainToll-Like Receptor 4 Deficiency Impairs Motor Coordination.X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner.Targeted ANP32E mutant mice do not demonstrate obvious movement defectsAcyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity.Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering.Relapsing-remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells.Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α.The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism.The progeroid gene BubR1 regulates axon myelination and motor function.Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with agingThe familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous systemBrain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice.Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin miceTau reduction does not prevent motor deficits in two mouse models of Parkinson's diseaseLoss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease.Longitudinally extensive NMO spinal cord pathology produced by passive transfer of NMO-IgG in mice lacking complement inhibitor CD59.RNAi or overexpression: alternative therapies for Spinocerebellar Ataxia Type 1A novel mouse model of a patient mucolipidosis II mutation recapitulates disease pathologyAge-related behavioral phenotype of an astrocytic monoamine oxidase-B transgenic mouse model of Parkinson's disease.Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencingNonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7.Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAEHuntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.Progression of ulcerative dermatitis lesions in C57BL/6Crl mice and the development of a scoring system for dermatitis lesionsIsolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy.Muscle-specific expression of LARGE restores neuromuscular transmission deficits in dystrophic LARGE(myd) micePPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7Role of proteolytic activation of protein kinase Cδ in the pathogenesis of prion disease.Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.Valnoctamide Inhibits Cytomegalovirus Infection in Developing Brain and Attenuates Neurobehavioral Dysfunctions and Brain Abnormalities.Assessment of ataxia phenotype in a new mouse model of galactose-1 phosphate uridylyltransferase (GALT) deficiency.Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease.A Simple Alternative to Stereotactic Injection for Brain Specific Knockdown of miRNA.Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.Protein arginylation targets alpha synuclein, facilitates normal brain health, and prevents neurodegeneration
P2860
Q27310161-97F44557-D217-45F2-A238-3B6951C2CB4BQ27313529-1FC8A00B-7CED-4B77-84D3-738BAC8F5B45Q27317003-51BB3B3A-1B39-4CDE-9677-6E047AF50E5DQ27320069-238073EF-AF88-4BF3-875F-8A7C5E6C528EQ30447826-923D49AD-7310-43D1-81C5-0DC7ACA8F693Q30566719-2E99F35C-FFB8-4E8C-AF97-8891FA81639AQ30574747-398200F6-C259-4269-9AD0-7C989BA1978EQ30613057-B1CE99E7-3826-4F92-8E16-52F0D5F6D560Q30650481-2A48BF79-DEEA-4910-A0DF-0CEE3569FD65Q30833258-39AA128F-B0E1-4AD9-A560-556940905BF2Q30840029-4FD601CB-8230-4763-AF4A-D55E02055F2AQ33639450-C8C230B6-CD02-430C-B3FA-7A739E431199Q33746273-93059237-0027-4D29-9632-02484B3011ABQ33929052-9C9FED9D-697D-40A9-908E-E10B30E0AF9DQ34103418-59C5CB14-9342-47D3-92B5-C18B5180F644Q34113712-58E080CC-C5E3-4548-A5F8-6CF1DCF8A296Q34144429-A340C20C-C99B-4B43-B4CE-5EDB5E6E298DQ34173376-C29DB7E3-4854-4375-A6FC-4AA0420F0D3DQ34235172-D0F14072-1E0F-4814-8A9E-F13F1847B979Q34244952-0A9BC7D9-7FA9-4831-AAB2-45759E7E7DDBQ34552247-15DEBE43-639C-4A18-BCD1-1CD4275142D5Q34672035-A43639A5-A74B-43C5-8AFF-189AC732BDB5Q35618581-2123C8D5-D2C0-43E9-9601-EDC22B2005B7Q35669064-CA178B6C-96B6-4BD1-B3F8-229F0E470807Q35946323-9FDD886F-C425-4352-BB67-2B8B2A1FE383Q36248637-32A5BF48-C584-4F24-8347-165B81DC628FQ36456670-4B389CD6-92F9-450F-BC8B-325381AA18FDQ36559993-8FA9E78C-986E-4B6D-B436-AA5A399FB8EEQ36575566-4C5B7887-C596-4FE8-9E6C-299F0573AE88Q36580728-B55483BC-2255-4DEA-948D-19BBB753CD34Q37184038-4587D9F7-5CA7-43EB-B183-F6B601D38610Q37310305-DD8329CF-B628-4C4C-B512-3769BA43EEEAQ38288366-FB94A117-8A06-4EE9-92AE-4B95DCADD0B1Q38602233-5EA1AD9D-B490-4A03-8622-8B0C222D4F46Q38718373-503ACC8F-6441-468D-A554-786211DE8CF5Q39248160-D7D5BA62-E0EE-45AD-A7D3-60FBD3B21173Q40067437-62666224-C896-4B47-BB6B-36E2A28F3734Q40094921-9239C375-2D0B-4F00-AB07-4616E9F8A1C8Q40329109-A7E5E223-E923-439F-A10B-6752071DF8AEQ41202092-2AFB00D2-0388-4022-943A-A58CABE61FC3
P2860
A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
A simple composite phenotype s ...... e models of cerebellar ataxia.
@en
type
label
A simple composite phenotype s ...... e models of cerebellar ataxia.
@en
prefLabel
A simple composite phenotype s ...... e models of cerebellar ataxia.
@en
P2093
P356
P1476
A simple composite phenotype s ...... se models of cerebellar ataxia
@en
P2093
Albert R La Spada
Stephan J Guyenet
Stephanie A Furrer
Travis D Baughan
Vincent M Damian
P356
10.3791/1787
P577
2010-05-21T00:00:00Z