Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.
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Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interactionThe haemopoietic stem cell: between apoptosis and self renewalPharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansionImmunological Basis of Bone Marrow Failure after Allogeneic Hematopoietic Stem Cell TransplantationThe role of Smad signaling in hematopoiesis.The role of the Fanconi anemia network in the response to DNA replication stress.Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineageExpansion of cord blood CD34 cells in presence of zVADfmk and zLLYfmk improved their in vitro functionality and in vivo engraftment in NOD/SCID mouseHematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic stem cells of wild type but not Id1 deficient mice.TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.Apoptotic mechanisms in the control of erythropoiesis.Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.In vitro and in vivo expansion of hematopoietic stem cells.HOXB4's road map to stem cell expansion.Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.Allogeneic hematopoietic cell transplantation for myelofibrosis in the era of JAK inhibitors.Concise review: the bone marrow niche as a target of graft versus host disease.Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis.Tumor necrosis factor alpha induces senescence and chromosomal instability in human leukemic cells.Interleukin 32 promotes hematopoietic progenitor expansion and attenuates bone marrow cytotoxicity.TNF-α has tropic rather than apoptotic activity in human hematopoietic progenitors: involvement of TNF receptor-1 and caspase-8.Ex vivo expansion of cord blood progenitors impairs their short-term and long-term repopulating activity associated with transcriptional dysregulation of signalling networks.TNFalpha stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells.Dynamic interaction networks in a hierarchically organized tissue.TNF-α-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma.Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptorsActivation and crosstalk between TNF family receptors in umbilical cord blood cells is not responsible for loss of engraftment capacity following culture.Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient micePre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells.Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity.Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFα signaling.Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation.
P2860
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P2860
Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Self-renewal of multipotent lo ...... is factor receptor activation.
@en
type
label
Self-renewal of multipotent lo ...... is factor receptor activation.
@en
prefLabel
Self-renewal of multipotent lo ...... is factor receptor activation.
@en
P2093
P2860
P50
P356
P1476
Self-renewal of multipotent lo ...... sis factor receptor activation
@en
P2093
C M Högerkorp
J Adolfsson
V Ramsfjell
P2860
P304
P356
10.1084/JEM.194.7.941
P407
P577
2001-10-01T00:00:00Z