Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

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Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease.Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase.

P2860

Q39387270-6D079F5A-6624-4B60-8298-4171A87F3B31 Q47904028-BC5C65BE-110B-4979-8C3F-2B4F2F73A6DC

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Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

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http://www.wikidata.org/entity/Q41859179

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

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Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

@en

type

Item

label

Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

@en

prefLabel

Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

@en

P1476

Deletion of Lkb1 in adult mice results in body weight reduction and lethality

@en

P2093

Tizhong Shan

http://www.w3.org/2001/XMLSchema#string

Yan Xiong

http://www.w3.org/2001/XMLSchema#string

P2860

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3

LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes

Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons

Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice.

LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis.

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.

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srep36561

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36561

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scholarly article

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10.1038/SREP36561

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English

P478

http://www.w3.org/2001/XMLSchema#string

P50

Shihuan Kuang

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2016-11-08T00:00:00Z

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27824128

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P932

5099919

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Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

about

P2860

P2860

Deletion of Lkb1 in adult mice results in body weight reduction and lethality.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P478

P50

P577

P698

P932