AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
about
IgH chain class switch recombination: mechanism and regulationActivation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution.AID/APOBEC deaminases and cancerAID and Apobec3G haphazard deamination and mutational diversityATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombinationAID-initiated DNA lesions are differentially processed in distinct B cell populations.Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.Overlapping hotspots in CDRs are critical sites for V region diversificationMismatch-mediated error prone repair at the immunoglobulin genes.Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells.Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination.AIDing antibody diversity by error-prone mismatch repair.A structural basis for the biochemical behavior of activation-induced deoxycytidine deaminase class-switch recombination-defective hyper-IgM-2 mutantsImmunoglobulin class-switch DNA recombination: induction, targeting and beyond.Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers.UNG protects B cells from AID-induced telomere loss.C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversionDifferential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylaseActivation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombinationDNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination.A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger's CATalytic Pocket.Activation-induced cytidine deaminase in antibody diversification and chromosome translocation.AID and APOBEC deaminases: balancing DNA damage in epigenetics and immunity.Engineering and optimising deaminase fusions for genome editing.Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus.YY1 controls immunoglobulin class switch recombination and nuclear activation-induced deaminase levels.Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombinationMismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching.
P2860
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P2860
AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
AID recruits UNG and Msh2 to I ...... he AID C terminus [corrected].
@en
type
label
AID recruits UNG and Msh2 to I ...... he AID C terminus [corrected].
@en
prefLabel
AID recruits UNG and Msh2 to I ...... he AID C terminus [corrected].
@en
P2093
P2860
P356
P1476
AID recruits UNG and Msh2 to I ...... he AID C terminus [corrected].
@en
P2093
Anna J Ucher
Erin K Linehan
Janet Stavnezer
Lyne Khair
Mrinmay Chakrabarti
Sanjay Ranjit
P2860
P304
P356
10.4049/JIMMUNOL.1101406
P407
P577
2011-07-29T00:00:00Z