The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling.
about
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resectionDNA end resection: many nucleases make light workSae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks.Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.Phosphatase complex Pph3/Psy2 is involved in regulation of efficient non-homologous end-joining pathway in the yeast Saccharomyces cerevisiae.Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand BreaksSae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures.Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance.Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.A novel checkpoint and RPA inhibitory pathway regulated by Rif1Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenanceIdentification of novel and conserved Populus tomentosa microRNA as components of a response to water stress.Synthetic viability genomic screening defines Sae2 function in DNA repair.Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends.Phosphorylation of Sae2 Mediates Forkhead-associated (FHA) Domain-specific Interaction and Regulates Its DNA Repair Function.Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 ActivityMRX-dependent DNA damage response to short telomeres.Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining.Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture systemA novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 geneFunctional interactions between Sae2 and the Mre11 complex.The cellular response to chromosome breakage.Unique and overlapping functions of the Exo1, Mre11 and Pso2 nucleases in DNA repair.Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycleDNA Replication Stress Phosphoproteome Profiles Reveal Novel Functional Phosphorylation Sites on Xrs2 in Saccharomyces cerevisiaeDNA damage response at functional and dysfunctional telomeresMechanism and regulation of DNA end resection in eukaryotesDeacetylase Rpd3 facilitates checkpoint adaptation by preventing Rad53 overactivation.Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.Analysis of chromatin remodeling during formation of a DNA double-strand break at the yeast mating type locus.Mechanisms and regulation of DNA end resection.Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.Coupling end resection with the checkpoint response at DNA double-strand breaks.
P2860
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P2860
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The Saccharomyces cerevisiae S ...... damage checkpoint signalling.
@en
type
label
The Saccharomyces cerevisiae S ...... damage checkpoint signalling.
@en
prefLabel
The Saccharomyces cerevisiae S ...... damage checkpoint signalling.
@en
P2093
P2860
P356
P1433
P1476
The Saccharomyces cerevisiae S ...... damage checkpoint signalling.
@en
P2093
Davide Mantiero
Giovanna Lucchini
Michela Clerici
P2860
P304
P356
10.1038/SJ.EMBOR.7400593
P577
2006-02-01T00:00:00Z