Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

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Relative Movements of Domains in Large Molecules of the Immune System.Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity.

P2860

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Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

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http://www.wikidata.org/entity/Q41970542

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2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

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type

Item

label

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

@en

prefLabel

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

@en

P1476

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

@en

P2093

Dmitry M Gakamsky

http://www.w3.org/2001/XMLSchema#string

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Mechanisms behind functional avidity maturation in T cells

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex

Profound block in thymocyte development in mice lacking p56lck

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex

CDR3 loop flexibility contributes to the degeneracy of TCR recognition

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation.

Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling.

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16-22

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.IMLET.2013.11.005

http://www.w3.org/2001/XMLSchema#string

P433

1-2

http://www.w3.org/2001/XMLSchema#string

P478

157

http://www.w3.org/2001/XMLSchema#string

P50

Rose Zamoyska

Jessica G Borger

P577

2013-11-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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258828453

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24263053

http://www.w3.org/2001/XMLSchema#string

P932

3931270

http://www.w3.org/2001/XMLSchema#string

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

about

P2860

P2860

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932