Transmembrane-truncated alphavbeta3 integrin retains high affinity for ligand binding: evidence for an 'inside-out' suppressor?
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Crystal structure of the extracellular segment of integrin alpha Vbeta3Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectinInvolvement of transmembrane domain interactions in signal transduction by alpha/beta integrinsCrystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragmentDirect Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communicationDefinition of an unexpected ligand recognition motif for alphav beta6 integrin.Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins.Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformersInside-out regulation of L1 conformation, integrin binding, proteolysis, and concomitant cell migration.Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function.Integrin activation takes shape.Integrin structure: new twists and turns in dynamic cell adhesion.Integrins, cations and ligands: making the connection.Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin.Integrin signaling in malignant melanoma.Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinaseThree-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin.Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrinsThe structure and function of platelet integrins.Talin and kindlin: the one-two punch in integrin activation.Matched rabbit monoclonal antibodies against αv-series integrins reveal a novel αvβ3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.The ability of integrin alpha(v)beta(3) To function as a receptor for foot-and-mouth disease virus is not dependent on the presence of complete subunit cytoplasmic domains.Functional characterization of integrin alpha6beta4 adhesion interactions using soluble integrin constructs reveals the involvement of different functional domains in the beta4 subunit.Integrin cross-talk in endothelial cells is regulated by protein kinase A and protein phosphatase 1.In vivo imaging of integrin alpha v beta 3 expression using fluorescence-mediated tomography.Immunohistochemical screening for beta6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro.Production of recombinant soluble human integrin alpha4beta1.Mechanisms and consequences of affinity modulation of integrin alpha(V)beta(3) detected with a novel patch-engineered monovalent ligand.Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.Generation of a minimal alpha5beta1 integrin-Fc fragment.The eighth FIII domain of human fibronectin promotes integrin alpha5beta1 binding via stabilization of the ninth FIII domain.Dynamic change in the distribution of alpha5beta1 integrin on isolated ventral membrane: effect of divalent cation species.A 50-A separation of the integrin alpha v beta 3 extracellular domain C termini reveals an intermediate activation state.De novo expression of the integrin alpha5beta1 regulates alphavbeta3-mediated adhesion and migration on fibrinogen.Activation mechanisms of αVβ3 integrin by binding to fibronectin: A computational study.On the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation.
P2860
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P2860
Transmembrane-truncated alphavbeta3 integrin retains high affinity for ligand binding: evidence for an 'inside-out' suppressor?
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@en
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@nl
type
label
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@en
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@nl
prefLabel
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@en
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@nl
P2093
P2860
P356
P1433
P1476
Transmembrane-truncated alphav ...... or an 'inside-out' suppressor?
@en
P2093
Diefenbach B
Goodman SL
Luckenbach GA
P2860
P304
P356
10.1042/BJ3300861
P407
P478
330 ( Pt 2)
P577
1998-03-01T00:00:00Z