Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
about
CSIG inhibits PTEN translation in replicative senescenceNuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent mannerThe ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localizationNuclear PI3K signaling in cell growth and tumorigenesisThe PTEN Long N-tail is intrinsically disordered: increased viability for PTEN therapyNuclear PTEN levels and G2 progression in melanoma cellsPTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppressionNuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifsDecrease in PTEN and increase in Akt expression and neuron size in aged rat spinal cord.Pten regulates development and lactation in the mammary glands of dairy cows.AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressorAutophagy regulation in cancer development and therapy.Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma.Prognostic significance of PTEN, Ki-67 and CD44s expression patterns in gastrointestinal stromal tumorsPTEN regulates PDGF ligand switch for β-PDGFR signaling in prostate cancerPTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome.PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).A Novel Mechanism of PPARgamma Regulation of TGFbeta1: Implication in Cancer BiologyATP modulates PTEN subcellular localization in multiple cancer cell lines.The PTEN-Akt pathway impacts the integrity and composition of mitotic centrosomesPortrait of PTEN: messages from mutant mice.Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cellsGermline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function.PTEN: a new guardian of the genome.A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.Horizon scanning for novel therapeutics for the treatment of prostate cancer.PTEN in DNA damage repair.Is Cytoplasmic PTEN a Specific Target for Neuronal Survival?Combating trastuzumab resistance by targeting thioredoxin-1/PTEN interaction.Reduced PTEN expression and overexpression of miR-17-5p, -19a-3p, -19b-3p, -21-5p, -130b-3p, -221-3p and -222-3p by glioblastoma stem-like cells following irradiation.Regulation of PTEN degradation and NEDD4-1 E3 ligase activity by Numb.Semaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesis.ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization.Autophagic homeostasis is required for the pluripotency of cancer stem cells.Cell Cycle Control by PTEN.Thalidomide decreases gelatinase production by malignant B lymphoid cell lines through disruption of multiple integrin-mediated signaling pathways.MicroRNA-17-92 significantly enhances radioresistance in human mantle cell lymphoma cells.Phosphatidylinositol 3-kinase inhibitor(LY294002) induces apoptosis of human nasopharyngeal carcinoma in vitro and in vivo.The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML networkA short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth.
P2860
Q24320241-2BF1F6EE-3929-4E38-9B47-C62F65B998BDQ24337323-1AFD8A04-C740-47FF-8547-2841270DD7FFQ24650856-88255D74-E160-4A4E-8EAC-18E4B59F032BQ26859127-C7D1EBA2-DCC5-4CC4-A772-4AB1789C207BQ28299026-86D1E9F8-5E28-4BFA-BBD7-22F6CA03B0E6Q28391204-4E22456F-A750-49E9-93DF-5992B02E2A25Q28505099-EA542726-ED84-4847-90FA-9DAF3B776D55Q28564702-19B397E7-F0F9-49C7-96A7-4F5ECE001D66Q33823258-17F98EC2-6873-4317-B56F-BFACA2C5B248Q33882672-07CB73EF-AF6A-492F-9448-5CB12FE9A889Q34722525-771800C9-6DFB-4711-8BB6-685848EA7A2DQ35232272-69D22451-5E6B-435A-8671-DD51CA3AC0A0Q35235757-D716F402-2AA6-43C8-8729-8C0338C40BDEQ35886697-7100889C-35D7-4966-BF23-95872F3C8777Q35952035-3FCB794C-59AD-44F0-8428-879398AD3EA2Q36361389-8E53CF61-30D8-41C3-BD58-694AD30BAB26Q36497447-28C8AC78-5AA1-43C1-8053-157500506731Q36743890-9417D4C5-E2DD-4454-90A5-31139D1F10B6Q36851633-827A0779-B9B8-43C1-AD4C-3BD3B8D26A2CQ36906204-A7252C07-6E4E-4D1F-ABF3-7B14A3931ABFQ37059129-B08AEDC1-E2FB-43C7-92A9-ED09CFDC7CB8Q37203000-0E7FC829-C3FB-4DC2-A704-7AB38F464290Q37252731-39CE8194-9370-4A5E-A8D0-F38FDB9A8ED9Q37270432-0A2937F3-C400-41B7-AA2F-308CB8849CCCQ37626395-DD823267-A285-4B54-846C-95CC53DC670BQ37792060-6FCE6DF4-66B6-4D6D-B9AA-277285B71FC7Q37977769-E90E006A-19F1-40F5-9A01-302B1DCB2D28Q38266259-1E39297E-F631-4573-AE47-262044E58281Q38812090-48946869-C7B8-4121-BAA7-197DA5F8B8A5Q38815443-D5813A18-0CB6-4643-BF71-9C349766F18EQ38823123-42E5C25E-C4BA-456A-A8A6-E4E3C602B926Q39004667-F52FCC5B-2288-4BC2-9173-3D9C25F0F278Q39067694-E6B9951A-9DAC-479E-B382-EEB29A7F243AQ39120233-C1BB036D-8707-4131-96C1-FCAD6D1CFA18Q39365401-F677DA4F-FFF5-4746-AF15-E1FAA2311141Q39434628-A5580720-BAE2-48EC-81DC-7D204DE6B1A7Q39637411-1A68DECE-C43F-41CC-A249-B612B86E0CDCQ39711802-4E11A6AC-45F3-4AB6-924D-6E13856EEF63Q39948774-21A27D36-EB88-4077-A44F-00FDDF94F10DQ40184782-F7486488-8E40-48F2-AB2A-8131EFF0A858
P2860
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@en
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@nl
type
label
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@en
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@nl
prefLabel
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@en
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@nl
P2093
P2860
P1476
Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.
@en
P2093
Gary E Gallick
Juinn-Lin Liu
W K Alfred Yung
Xiaoyang Sheng
Zhenyu Mao
Zsuzsanna K Hortobagyi
P2860
P304
P356
10.1128/MCB.25.14.6211-6224.2005
P407
P577
2005-07-01T00:00:00Z