Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein.
about
NMR Meets Tau: Insights into Its Function and PathologyCharacteristics of Tau and Its Ligands in PET ImagingLegal but lethal: functional protein aggregation at the verge of toxicityPropagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Roles of tau protein in health and disease.Synthetic extreme environments: overlooked sources of potential biotechnologically relevant microorganisms.Proteopathic tau seeding predicts tauopathy in vivo.Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connectionsSensitive Detection of Proteopathic Seeding Activity with FRET Flow CytometryUnique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice.Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases.Protein phosphorylation in neurodegeneration: friend or foe?Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies.Conformation determines the seeding potencies of native and recombinant Tau aggregates.Amyloidogenesis of Tau protein.Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid.Identification of the Tau phosphorylation pattern that drives its aggregation.Simplified method to obtain enhanced expression of tau protein from E. coli and one-step purification by direct boiling.Inert and seed-competent tau monomers suggest structural origins of aggregation.
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P2860
Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-my
2013年学术文章
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name
Conformational features of tau ...... nmodified recombinant protein.
@en
Conformational features of tau ...... nmodified recombinant protein.
@nl
type
label
Conformational features of tau ...... nmodified recombinant protein.
@en
Conformational features of tau ...... nmodified recombinant protein.
@nl
prefLabel
Conformational features of tau ...... nmodified recombinant protein.
@en
Conformational features of tau ...... nmodified recombinant protein.
@nl
P2860
P50
P356
P1433
P1476
Conformational features of tau ...... nmodified recombinant protein.
@en
P2093
Olga A Morozova
P2860
P304
P356
10.1021/BI400866W
P407
P577
2013-09-27T00:00:00Z