MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
about
A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora BA microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingBuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignmentThe kinetochore interaction network (KIN) of ascomycetesThe Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingCell division: control of the chromosomal passenger complex in time and spaceThe current view for the silencing of the spindle assembly checkpointKNL1: bringing order to the kinetochoreKinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint responseBub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae.ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochoresOTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic KinasesCep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingStructural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint)Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin LigationMad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingThe human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochoresA Centromere-Signaling Network Underlies the Coordination among Mitotic EventsConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylationCharacterization of novel MPS1 inhibitors with preclinical anticancer activityConstruction of protein phosphorylation networks by data mining, text mining and ontology integration: analysis of the spindle checkpoint.Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment.An actin-dependent spindle position checkpoint ensures the asymmetric division in mouse oocytes.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylationInositol Pyrophosphate Kinase Asp1 Modulates Chromosome Segregation Fidelity and Spindle Function in Schizosaccharomyces pombe.Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast.Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation.Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis.Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex.Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progressionSTAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.
P2860
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P2860
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@en
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@nl
type
label
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@en
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@nl
prefLabel
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@en
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@nl
P2093
P2860
P356
P1433
P1476
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.
@en
P2093
Ching-Hui Yang
Yoshinori Watanabe
Yuji Tanno
Yuya Yamagishi
P2860
P2888
P304
P356
10.1038/NCB2515
P577
2012-06-03T00:00:00Z