Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR. - Wikidata - awgldk - TriplyDB

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

http://www.wikidata.org/entity/Q42174407

about

Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates Phage p1-derived artificial chromosomes facilitate heterologous expression of the FK506 gene cluster Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis Open resource metagenomics: a model for sharing metagenomic libraries Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.A functional screen for recovery of 4'-phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries.Natural product biosynthetic gene diversity in geographically distinct soil microbiomes.Mining the metabiome: identifying novel natural products from microbial communities.Reassembly of functionally intact environmental DNA-derived biosynthetic gene clusters Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products.Mining soil metagenomes to better understand the evolution of natural product structural diversity: pentangular polyphenols as a case study.Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters.Cloning and Heterologous Expression of the Grecocycline Biosynthetic Gene Cluster."Cre/loxP plus BAC": a strategy for direct cloning of large DNA fragment and its applications in Photorhabdus luminescens and Agrobacterium tumefaciens.Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.Cloning and Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyces Species Opportunities for synthetic biology in antibiotics: expanding glycopeptide chemical diversity.Discovery of microbial natural products by activation of silent biosynthetic gene clusters.Direct Capture Technologies for Genomics-Guided Discovery of Natural Products.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Culture-independent discovery of natural products from soil metagenomes.Recent advances in engineering nonribosomal peptide assembly lines.Genome Engineering and Modification Toward Synthetic Biology for the Production of Antibiotics.Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology.Toolbox for Antibiotics Discovery from Microorganisms.Arixanthomycins A-C: Phylogeny-guided discovery of biologically active eDNA-derived pentangular polyphenols Broad-Host-Range Expression Reveals Native and Host Regulatory Elements That Influence Heterologous Antibiotic Production in Gram-Negative Bacteria Multiplexed CRISPR/Cas9- and TAR-Mediated Promoter Engineering of Natural Product Biosynthetic Gene Clusters in Yeast.Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters.Diversity of Culturable Thermophilic Actinobacteria in Hot Springs in Tengchong, China and Studies of their Biosynthetic Gene Profiles.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens.TAR cloning and integrated overexpression of 6-demethylchlortetracycline biosynthetic gene cluster in Streptomyces aureofaciens.Yeast homologous recombination cloning leading to the novel peptides ambactin and xenolindicin.Rapid determination of the amino acid configuration of xenotetrapeptide.

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P2860

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

http://www.wikidata.org/entity/Q42174407

description

2010 nî lūn-bûn

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2010年论文

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2010年论文

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name

Cloning large natural product ...... usters back together with TAR.

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Cloning large natural product ...... usters back together with TAR.

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label

Cloning large natural product ...... usters back together with TAR.

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Cloning large natural product ...... usters back together with TAR.

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Cloning large natural product ...... usters back together with TAR.

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Cloning large natural product ...... usters back together with TAR.

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Cloning large natural product ...... usters back together with TAR.

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Dimitris Kallifidas

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Jeffrey H Kim

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John D Bauer

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Paula Y Calle

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Sean F Brady

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Zhiyang Feng

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P2860

One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome

The Uncultured Microbial Majority

Molecular cloning and physical mapping of the daptomycin gene cluster from Streptomyces roseosporus

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

Genome sequencing in microfabricated high-density picolitre reactors

GeneMark.hmm: new solutions for gene finding

Dynamics of Pseudomonas aeruginosa genome evolution

Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome

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10.1002/BIP.21450

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9

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93

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2010-09-01T00:00:00Z

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