Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster. - Wikidata - awgldk - TriplyDB

Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.

Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.

http://www.wikidata.org/entity/Q42439390

about

Recent Advances in Understanding and Engineering Polyketide Synthesis High-throughput metagenomic technologies for complex microbial community analysis: open and closed formats Biocatalysts and small molecule products from metagenomic studies Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete Cloning and characterization of an environmental DNA-derived gene cluster that encodes the biosynthesis of the antitumor substance BE-54017.Discovery of the lomaiviticin biosynthetic gene cluster in Salinispora pacifica Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.eSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes.Natural product biosynthetic gene diversity in geographically distinct soil microbiomes.Reassembly of functionally intact environmental DNA-derived biosynthetic gene clusters Rapid characterization and engineering of natural product biosynthetic pathways via DNA assembler Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis Inhibition of the growth of Bacillus subtilis DSM10 by a newly discovered antibacterial protein from the soil metagenome.Reinvigorating natural product combinatorial biosynthesis with synthetic biology Recent advances in the discovery and development of marine microbial natural products."Cre/loxP plus BAC": a strategy for direct cloning of large DNA fragment and its applications in Photorhabdus luminescens and Agrobacterium tumefaciens.Bioprospecting potential of the soil metagenome: novel enzymes and bioactivities Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.Biotechnology of polyketides: new breath of life for the novel antibiotic genetic pathways discovery through metagenomics Cloning and Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyces Species The role of transcription in heterologous expression of polyketides in bacterial hosts.Direct Capture Technologies for Genomics-Guided Discovery of Natural Products.Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products.Culture-independent discovery of natural products from soil metagenomes.Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases.Sampling Terrestrial Environments for Bacterial Polyketides.Production of α-cuprenene in Xanthophyllomyces dendrorhous: a step closer to a potent terpene biofactory.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.The microbial cell factory.Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes.TAR cloning and integrated overexpression of 6-demethylchlortetracycline biosynthetic gene cluster in Streptomyces aureofaciens.HEx: A heterologous expression platform for the discovery of fungal natural products.Fluostatins M-Q Featuring a 6-5-6-6 Ring Skeleton and High Oxidized A-Rings from Marine Streptomyces sp. PKU-MA00045.Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines.Marine Bacterial Aromatic Polyketides From Host-Dependent Heterologous Expression and Fungal Mode of Cyclization

P2860

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P2860

Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.

http://www.wikidata.org/entity/Q42439390

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Fluostatins produced by the he ...... ived type II PKS gene cluster.

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Fluostatins produced by the he ...... ived type II PKS gene cluster.

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type

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Fluostatins produced by the he ...... ived type II PKS gene cluster.

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Fluostatins produced by the he ...... ived type II PKS gene cluster.

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Fluostatins produced by the he ...... ived type II PKS gene cluster.

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Journal of the American Chemical Society

P1476

Fluostatins produced by the he ...... ived type II PKS gene cluster.

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P2093

Jeff H Kim

http://www.w3.org/2001/XMLSchema#string

Sean F Brady

http://www.w3.org/2001/XMLSchema#string

Zhiyang Feng

http://www.w3.org/2001/XMLSchema#string

P2860

The Uncultured Microbial Majority

Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules.

Prokaryotic diversity--magnitude, dynamics, and controlling factors.

A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms.

Highly selective isolation of human DNAs from rodent-human hybrid cells as circular yeast artificial chromosomes by transformation-associated recombination cloning.

The biosynthetic logic of polyketide diversity.

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

An environmental DNA-derived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin.

High diversity in DNA of soil bacteria.

A direct route to fluostatin C by a fascinating Diels-Alder reaction.

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11902-11903

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scholarly article

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10.1021/JA104550P

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34

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132

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2010-09-01T00:00:00Z

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45535275

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20690632

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