Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation.
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Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cellsProtein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingPhosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosisIrod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosisNaringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytesEstablishment of okadaic acid resistant cell clones using a cDNA expression library.An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease.The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53.Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressActions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits.Nuclear and mitochondrial apoptotic pathways of p53.ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation.Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigenThe natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters.Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response.GENE EXPRESSION PROFILING OF HUMAN LIVER CARCINOMA (HepG2) CELLS EXPOSED TO THE MARINE TOXIN OKADAIC ACID.The p53 family and programmed cell deathA modified p53 enhances apoptosis in sarcoma cell lines mediated by doxorubicinEffect of Lecithin on d-Galactosamine Induced Hepatotoxicity Through Mitochondrial Pathway Involving Bcl-2 and Bax.The protective mechanism of schisandrin A in d-galactosamine-induced acute liver injury through activation of autophagy.Transcriptional cross talk between NF-kappaB and p53.Okadaic acid and dinophysis toxin 2 have differential toxicological effects in hepatic cell lines inducing cell cycle arrest, at G0/G1 or G2/M with aberrant mitosis depending on the cell line.Induction of p53-independent apoptosis by simian virus 40 small t antigen.Myrtenal ameliorates diethylnitrosamine-induced hepatocarcinogenesis through the activation of tumor suppressor protein p53 and regulation of lysosomal and mitochondrial enzymes.B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster.p53 Plays an important role in cell fate determination after exposure to microcystin-LR.Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-kappaB- and p53-regulated gene targets.BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells.Iron deprivation induces apoptosis independently of p53 in human and murine tumour cells.p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest.Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis.Protective Role of Catechin on d-Galactosamine Induced Hepatotoxicity Through a p53 Dependent Pathway.The p53 network.Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F0-ATP synthase.Modulation of hippocampal calcium signalling and plasticity by serine/threonine protein phosphatases.Involment of p53, Bax, and Bcl-2 pathway in microcystins-induced apoptosis in rat testis.Cell-cycle control in cell-biomaterial interactions: expression of p53 and Ki67 in human umbilical vein endothelial cells in direct contact and extract testing of biomaterials.
P2860
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P2860
Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@en
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@nl
type
label
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@en
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@nl
prefLabel
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@en
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@nl
P2093
P2860
P356
P1476
Inhibition of protein phosphat ...... bsence of p53 transactivation.
@en
P2093
P2860
P304
15220-15226
P356
10.1074/JBC.272.24.15220
P407
P577
1997-06-01T00:00:00Z