Basic fibroblast growth factor stimulates surface expression and activity of Na(+)/H(+) exchanger NHE3 via mechanism involving phosphatidylinositol 3-kinase.
about
Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosisNa+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3Quantitation of plasma membrane expression of a fusion protein of Na/H exchanger NHE3 and green fluorescence protein (GFP) in living PS120 fibroblasts.NHERF: targeting and trafficking membrane proteins.Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells.NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid.NHE3 activity is dependent on direct phosphoinositide binding at the N terminus of its intracellular cytosolic region.Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport.Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.The emerging role of PDZ adapter proteins for regulation of intestinal ion transport.Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells.Role of Fyn and PI3K in H2O2-induced inhibition of apical Cl-/OH- exchange activity in human intestinal epithelial cellsAlpha2-adrenergic receptors attenuate secretagogue-induced endocytosis and promote exocytosis of intestinal NHE2 and NHE3.The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking.Different ionic conditions prompt NHE2 and NHE3 translocation to the plasma membrane.Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.Lysophosphatidic acid stimulates brush border Na+/H+ exchanger 3 (NHE3) activity by increasing its exocytosis by an NHE3 kinase A regulatory protein-dependent mechanism.Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells.Half-lives of plasma membrane Na(+)/H(+) exchangers NHE1-3: plasma membrane NHE2 has a rapid rate of degradation.Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes.Subcellular redistribution of the renal betaine transporter during hypertonic stress.Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3.Mechanisms of lysophosphatidic acid (LPA) mediated stimulation of intestinal apical Cl-/OH- exchange.Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3.cAMP-dependent activation of the renal-specific Na+-K+-2Cl- cotransporter is mediated by regulation of cotransporter trafficking.Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent.Ion and diuretic specificity of chimeric proteins between apical Na(+)-K(+)-2Cl(-) and Na(+)-Cl(-) cotransporters.Trafficking Ion Transporters to the Apical Membrane of Polarized Intestinal Enterocytes.
P2860
Q24294203-589221AF-9814-4290-904E-E138DFC24534Q28365699-565C9709-4F92-4A5E-9062-84502A1DE3ADQ30944653-FBC82870-0807-4965-91BD-140CA3B8575DQ31955806-E999D599-9A5E-4548-B01B-E0ACA6568A8AQ34043225-9E3876BE-391C-4E5E-B02D-F75354AE7619Q34116039-4561A9B1-4EB5-47EE-8672-3A3248AEC666Q34251172-C1DD2905-FF23-49C1-AE92-A95751973762Q35266484-7BFA840A-3B81-4681-81B0-B841B71B9695Q35322212-38B89F64-893D-4EDC-955B-F789C63FC39AQ35340637-39878AD3-CFB4-48C8-87E2-5C9C50DE983AQ35754862-C30FEB47-6BC8-4979-8620-27E97CB0A4DEQ36518490-B1C9FF1D-0471-4039-9881-343733CD4E49Q36699729-51F0F890-BFD9-4FDB-B9B8-EDB5EAC88FE5Q37169951-3CFEE6E4-47CF-43FE-9DBC-A4D10E6A0BEAQ37312866-97D37BCE-BDF1-46AE-9EBB-ABC82695AAFCQ37689977-7673576D-0ACD-4038-AE84-949CF3A1DCBBQ40170700-B98583C7-6A82-4E0A-8AA2-354C30F02632Q40258022-752B94CA-B794-4CCC-8126-20BBCCC3A815Q40609831-1F6D6538-955C-4106-92D8-EDC707FC010EQ40669337-552D636B-E3BA-4299-AD73-62E3BFA8DD44Q40710828-69AF4AE5-0F7A-409D-A42D-8736900B45D9Q40769955-BFF023E2-386F-457F-9A4F-6E101BD5D5ACQ41001492-97759A0F-4333-43F6-BDD6-9DA391857021Q42162682-D55D938F-578B-4BF6-888D-9A77E81C919FQ42504933-90151907-5ECD-44B5-8A25-70C69BFA1A9AQ42915300-063F4731-1CD7-49A4-BCA4-7D6BFF92B316Q43720111-306F27DB-ABDA-40B7-B521-2262F79AEA87Q44327191-033EC186-B349-486F-98A8-314F0C33A167Q44772868-90E9687C-375D-48F5-8D61-40DD3595B735Q44901016-8269E253-B823-4362-9647-2326B4C52C1DQ47144215-404A9C3F-0372-490F-AE6A-BB44B14D1812
P2860
Basic fibroblast growth factor stimulates surface expression and activity of Na(+)/H(+) exchanger NHE3 via mechanism involving phosphatidylinositol 3-kinase.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Basic fibroblast growth factor stimulates surface expression and activity of Na
@nl
Basic fibroblast growth factor ...... phosphatidylinositol 3-kinase.
@en
type
label
Basic fibroblast growth factor stimulates surface expression and activity of Na
@nl
Basic fibroblast growth factor ...... phosphatidylinositol 3-kinase.
@en
prefLabel
Basic fibroblast growth factor stimulates surface expression and activity of Na
@nl
Basic fibroblast growth factor ...... phosphatidylinositol 3-kinase.
@en
P2093
P2860
P356
P1476
Basic fibroblast growth factor ...... phosphatidylinositol 3-kinase.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.11.8133
P407
P577
2000-03-01T00:00:00Z