Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor.
about
Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repressionA new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elementsNuclear receptor corepressorsA transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptorNuclear thyroid hormone receptorsNuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormoneThe nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor.Cloning and characterization of two novel thyroid hormone receptor beta isoforms.Unbinding of retinoic acid from its receptor studied by steered molecular dynamicsThe N-terminal region (A/B) of rat thyroid hormone receptors alpha 1, beta 1, but not beta 2 contains a strong thyroid hormone-dependent transactivation functionMechanisms of thyroid hormone actionGenome-wide binding patterns of thyroid hormone receptor beta.Thyroid hormone and leptin in the testis.New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.Direct modulation of simian virus 40 late gene expression by thyroid hormone and its receptor.Maternal high-fat diet modulates the fetal thyroid axis and thyroid gene expression in a nonhuman primate model.The in vivo role of nuclear receptor corepressors in thyroid hormone action.Genetic dissection of thyroid hormone receptor beta: identification of mutations that separate hormone binding and transcriptional activation.Both thyroid hormone and 9-cis retinoic acid receptors are required to efficiently mediate the effects of thyroid hormone on embryonic development and specific gene regulation in Xenopus laevisConstitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.Functional evidence for ligand-dependent dissociation of thyroid hormone and retinoic acid receptors from an inhibitory cellular factorA novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene.Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor.Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptorNovel location and function of a thyroid hormone response element.A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains.A novel role for helix 12 of retinoid X receptor in regulating repression.Transcriptional silencing by unliganded thyroid hormone receptor beta requires a soluble corepressor that interacts with the ligand-binding domain of the receptor.A novel cytoplasmic adaptor for retinoic acid receptor (RAR) and thyroid receptor functions as a Derepressor of RAR in the absence of retinoic acidThe N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.The ligand-binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation.The thyroid hormone receptor gene (c-erbA alpha) is expressed in advance of thyroid gland maturation during the early embryonic development of Xenopus laevisThyroid hormone receptor can modulate retinoic acid-mediated axis formation in frog embryogenesis.Negative regulation of transcription in eukaryotes.The conserved ninth C-terminal heptad in thyroid hormone and retinoic acid receptors mediates diverse responses by affecting heterodimer but not homodimer formation.
P2860
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P2860
Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@en
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@nl
type
label
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@en
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@nl
prefLabel
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@en
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@nl
P2093
P1433
P1476
Thyroid hormone aporeceptor re ...... of the retinoic acid receptor.
@en
P2093
P304
P577
1989-12-01T00:00:00Z