Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases.
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Imaging alterations of cardiomyocyte cAMP microdomains in diseaseNuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signalingCalcium signals driven by single channel noiseSelective Phosphodiesterase 4B Inhibitors: A ReviewFRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cellsStriatal neurones have a specific ability to respond to phasic dopamine releasePhosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterasesPhosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in miceA compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytesInotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heartMechanisms of cyclic AMP compartmentation revealed by computational models.PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.Protein kinases A and C regulate receptor-mediated increases in cAMP in rabbit erythrocytes.Equilibrium between adenylyl cyclase and phosphodiesterase patterns adrenergic agonist dose-dependent spatiotemporal cAMP/protein kinase A activities in cardiomyocytes.Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle.β-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cellsConserved expression and functions of PDE4 in rodent and human heart.Ischemic preconditioning inhibits mitochondrial permeability transition pore opening through the PTEN/PDE4 signaling pathwayLocal control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca(2+)-transient.Enhanced cardiac function in Gravin mutant mice involves alterations in the β-adrenergic receptor signaling cascadeInterventricular differences in β-adrenergic responses in the canine heart: role of phosphodiesterases.A2B adenosine receptors inhibit superoxide production from mitochondrial complex I in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxinGlucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with IsoproterenolNitric Oxide Protects L-Type Calcium Channel of Cardiomyocyte during Long-Term Isoproterenol Stimulation in Tail-Suspended Rats.MRP4 and CFTR in the regulation of cAMP and β-adrenergic contraction in cardiac myocytesExperimental and mathematical analysis of cAMP nanodomains.Compartmentalization of beta-adrenergic signals in cardiomyocytes.Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel.Acute β-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays G(q)-induced transcriptional activationRoles of phosphodiesterases in the regulation of the cardiac cyclic nucleotide cross-talk signaling networkcGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardiumCalcium/calmodulin-dependent kinase II and nitric oxide synthase 1-dependent modulation of ryanodine receptors during β-adrenergic stimulation is restricted to the dyadic cleftCompartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases.Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.Green light to illuminate signal transduction events.Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Cyclic nucleotide compartmentalization: contributions of phosphodiesterases and ATP-binding cassette transporters.Decoding spatial and temporal features of neuronal cAMP/PKA signaling with FRET biosensors.Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.
P2860
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P2860
Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@en
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@nl
type
label
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@en
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@nl
prefLabel
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@en
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@nl
P2093
P50
P1433
P1476
Spatiotemporal dynamics of bet ...... s: role of phosphodiesterases.
@en
P2093
Aniella Abi-Gerges
Grégoire Vandecasteele
Jean-Luc Mazet
Jérôme Leroy
Marco Conti
Patrick Lechêne
Rodolphe Fischmeister
Viacheslav O Nikolaev
P304
P356
10.1161/CIRCRESAHA.107.167817
P577
2008-03-27T00:00:00Z