Inactivation of E2F3 results in centrosome amplification. - Wikidata - awgldk - TriplyDB

Inactivation of E2F3 results in centrosome amplification.

Inactivation of E2F3 results in centrosome amplification.

http://www.wikidata.org/entity/Q42588738

about

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis Signalling in the epidermis: the E2F cell cycle regulatory pathway in epidermal morphogenesis, regeneration and transformation Centrosome - a promising anti-cancer target Aberrant regulation of survivin by the RB/E2F family of proteins Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity Comparative analysis of E2F family member oncogenic activity.E2F3 is a mediator of DNA damage-induced apoptosis.PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.E2F activators signal and maintain centrosome amplification in breast cancer cells.Coregulation of FANCA and BRCA1 in human cells Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2 Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesis The G1 phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification.Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model.Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene.Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis.Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues.E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas Preventing the degradation of mps1 at centrosomes is sufficient to cause centrosome reduplication in human cells.The RB protein family in retinal development and retinoblastoma: new insights from new mouse models.Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosis The E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis.E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.An integrated view of cyclin E function and regulation Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.Orc1 controls centriole and centrosome copy number in human cells.Overexpression of miR-210, a downstream target of HIF1α, causes centrosome amplification in renal carcinoma cells.Lats2 is an essential mitotic regulator required for the coordination of cell division.miRNA-34b is directly involved in the aging of macrophages.Centrosome aberrations and chromosome instability contribute to tumorigenesis and intra-tumor heterogeneity

P2860

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P2860

Inactivation of E2F3 results in centrosome amplification.

http://www.wikidata.org/entity/Q42588738

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

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2003年论文

@zh

2003年论文

@zh-cn

name

Inactivation of E2F3 results in centrosome amplification.

@en

Inactivation of E2F3 results in centrosome amplification.

@nl

type

label

Inactivation of E2F3 results in centrosome amplification.

@en

Inactivation of E2F3 results in centrosome amplification.

@nl

prefLabel

Inactivation of E2F3 results in centrosome amplification.

@en

Inactivation of E2F3 results in centrosome amplification.

@nl

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S1535-6108(03)00083-7

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P1476

Inactivation of E2F3 results in centrosome amplification.

@en

P2093

Baidehi Maiti

http://www.w3.org/2001/XMLSchema#string

Cynthia Timmers

http://www.w3.org/2001/XMLSchema#string

Gustavo Leone

http://www.w3.org/2001/XMLSchema#string

Harold I Saavedra

http://www.w3.org/2001/XMLSchema#string

Kenji Fukasawa

http://www.w3.org/2001/XMLSchema#string

Rachel Altura

http://www.w3.org/2001/XMLSchema#string

Yukari Tokuyama

http://www.w3.org/2001/XMLSchema#string

P2860

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells

Centrosome amplification drives chromosomal instability in breast tumor development.

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins

E2f3 is critical for normal cellular proliferation

Delay of HeLa cell cleavage into interphase using dihydrocytochalasin B: retention of a postmitotic spindle and telophase disc correlates with synchronous cleavage recovery

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

Cyclin-dependent kinase control of centrosome duplication

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333-346

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10.1016/S1535-6108(03)00083-7

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4

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3

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12726860

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3033013

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