State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.
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The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunctionX-ray structures of LeuT in substrate-free outward-open and apo inward-open statesThe atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitorsAssessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study analyzing the neurotransmitter/Na+ symporter family.A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters.Ligand effects on cross-linking support a conformational mechanism for serotonin transport.Substrate-dependent proton antiport in neurotransmitter:sodium symporters.Functional characterization of a Na+-dependent dicarboxylate transporter from Vibrio cholerae.The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter.Structure-function studies of the SLC17 transporter sialin identify crucial residues and substrate-induced conformational changesIon/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters.Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue.Conformational rearrangements to the intracellular open states of the LeuT and ApcT transporters are modulated by common mechanismsSLC6 transporters: structure, function, regulation, disease association and therapeuticsMicroseconds simulations reveal a new sodium-binding site and the mechanism of sodium-coupled substrate uptake by LeuTThe rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters.Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.Functional reconstitution of SdcS, a Na+-coupled dicarboxylate carrier protein from Staphylococcus aureusMonitoring the function of membrane transport proteins in detergent-solubilized form.Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium SymportersSimulating the distance distribution between spin-labels attached to proteinsIdentification of a chloride ion binding site in Na+/Cl -dependent transporters.Molecular basis of essential amino acid transport from studies of insect nutrient amino acid transporters of the SLC6 family (NAT-SLC6)Ion-controlled conformational dynamics in the outward-open transition from an occluded state of LeuT.Knockdown of a nutrient amino acid transporter gene LdNAT1 reduces free neutral amino acid contents and impairs Leptinotarsa decemlineata pupationTwo Na+ Sites Control Conformational Change in a Neurotransmitter Transporter HomologMechanism for alternating access in neurotransmitter transporters.Chloride binding site of neurotransmitter sodium symporters.Control of serotonin transporter phosphorylation by conformational state.Identification of conformationally sensitive amino acids in the Na(+)/dicarboxylate symporter (SdcS).Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters.A conserved Na(+) binding site of the sodium-coupled neutral amino acid transporter 2 (SNAT2).Functional characterization of a Na(+)-coupled dicarboxylate transporter from Bacillus licheniformis.Identification of novel serotonin transporter compounds by virtual screening.A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.An intracellular interaction network regulates conformational transitions in the dopamine transporter.Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes.A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1.How do transporters couple solute movements?Transmembrane domain 8 of the {gamma}-aminobutyric acid transporter GAT-1 lines a cytoplasmic accessibility pathway into its binding pocket.
P2860
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P2860
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
State-dependent conformations ...... from Fusobacterium nucleatum.
@en
State-dependent conformations ...... from Fusobacterium nucleatum.
@nl
type
label
State-dependent conformations ...... from Fusobacterium nucleatum.
@en
State-dependent conformations ...... from Fusobacterium nucleatum.
@nl
prefLabel
State-dependent conformations ...... from Fusobacterium nucleatum.
@en
State-dependent conformations ...... from Fusobacterium nucleatum.
@nl
P2093
P2860
P50
P356
P1476
State-dependent conformations ...... r from Fusobacterium nucleatum
@en
P2093
Lihua Duan
Matthias Quick
Naomi R Goldberg
Thijs Beuming
P2860
P304
26444-26454
P356
10.1074/JBC.M602438200
P407
P577
2006-06-23T00:00:00Z