Mode of action of invasion-inhibitory antibodies directed against apical membrane antigen 1 of Plasmodium falciparum.
about
Novel approaches to identify protective malaria vaccine candidatesMolecular identification of a malaria merozoite surface sheddaseMechanisms of cellular invasion by intracellular parasitesStructure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory AntibodyHumoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity.An inhibitory antibody blocks interactions between components of the malarial invasion machinery.Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasionEpitope mapping of PfCP-2.9, an asexual blood-stage vaccine candidate of Plasmodium falciparum.Non-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay.Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodiesAdvances and challenges in malaria vaccine development.The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody.Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development.Structural basis of antigenic escape of a malaria vaccine candidateMalaria vaccines in development.Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth CohortAcquired antibodies to merozoite antigens in children from Uganda with uncomplicated or severe Plasmodium falciparum malaria.Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1.Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets.Blood-stage malaria vaccines - recent progress and future challenges.Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort.Searching for Achilles' heel: can rational design of malaria vaccines overcome antigenic diversity?Alanine mutagenesis of the primary antigenic escape residue cluster, c1, of apical membrane antigen 1.Plasmodium vivax ligand-receptor interaction: PvAMA-1 domain I contains the minimal regions for specific interaction with CD71+ reticulocytes.Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.EDiP: the Epitope Dilution Phenomenon. Lessons learnt from a malaria vaccine antigen and its applicability to polymorphic antigens.Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion
P2860
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P2860
Mode of action of invasion-inhibitory antibodies directed against apical membrane antigen 1 of Plasmodium falciparum.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@en
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@nl
type
label
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@en
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@nl
prefLabel
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@en
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@nl
P2093
P2860
P1476
Mode of action of invasion-inh ...... en 1 of Plasmodium falciparum.
@en
P2093
Alan W Thomas
David E Lanar
J David Haynes
J Kathleen Moch
Jeffrey D Snavely
Lisa A Ware
Sheetij Dutta
P2860
P304
P356
10.1128/IAI.73.4.2116-2122.2005
P407
P577
2005-04-01T00:00:00Z