Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.
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Molecular identification of a malaria merozoite surface sheddaseMerozoite surface proteins in red blood cell invasion, immunity and vaccines against malariaThe roles of intramembrane proteases in protozoan parasitesMechanisms of cellular invasion by intracellular parasitesPfRH2b specific monoclonal antibodies inhibit merozoite invasionMaking the cut: central roles of intramembrane proteolysis in pathogenic microorganismsThe crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis.Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory AntibodyThe structural basis for catalysis and substrate specificity of a rhomboid proteaseTwo Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malariaNovel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytesA Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasionExport of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasionGC-1 mRHBDD1 knockdown spermatogonia cells lose their spermatogenic capacity in mouse seminiferous tubulesA Trichomonas vaginalis Rhomboid Protease and Its Substrate Modulate Parasite Attachment and Cytolysis of Host CellsIntramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasiteHumoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity.Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum.Formation of the food vacuole in Plasmodium falciparum: a potential role for the 19 kDa fragment of merozoite surface protein 1 (MSP1(19))An inhibitory antibody blocks interactions between components of the malarial invasion machinery.Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasionPlasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole.Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii.Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodiesIntramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.Toxoplasma gondii transmembrane microneme proteins and their modular design.Functional analysis of rhomboid proteases during Toxoplasma invasion.The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody.An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion.Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysisIntramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication.Mononeme: a new secretory organelle in Plasmodium falciparum merozoites identified by localization of rhomboid-1 proteaseMalaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1Microneme rhomboid protease TgROM1 is required for efficient intracellular growth of Toxoplasma gondii.Cryptosporidium parvum rhomboid1 has an activity in microneme protein CpGP900 cleavage.Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets.Invasion factors are coupled to key signalling events leading to the establishment of infection in apicomplexan parasites.Structural comparison of substrate entry gate for rhomboid intramembrane peptidases.The moving junction of apicomplexan parasites: a key structure for invasion.
P2860
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P2860
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@en
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@nl
type
label
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@en
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@nl
prefLabel
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@en
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@nl
P2093
P2860
P1476
Distinct mechanisms govern pro ...... ein in apicomplexan pathogens.
@en
P2093
Artemio M Jongco
Chrislaine Withers-Martinez
Fiona Hackett
Michael J Blackman
Steven A Howell
P2860
P304
P356
10.1111/J.1365-2958.2005.04772.X
P407
P577
2005-09-01T00:00:00Z