Hematopoietic stem cell aging: mechanism and consequence.
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Unexplained anemia in the elderlyDNA Damage Response in Hematopoietic Stem Cell AgeingT cell ageing: effects of age on development, survival & functionLifespan extension by preserving proliferative homeostasis in DrosophilaAging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitorsDistinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.Cell therapy, a new standard in management of chronic critical limb ischemia and foot ulcer.Ginsenoside Rg1 enhances the resistance of hematopoietic stem/progenitor cells to radiation-induced aging in mice.Diminished quality of life and physical function in community-dwelling elderly with anemia.Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cellsEwing sarcoma gene Ews regulates hematopoietic stem cell senescence.Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress.Measuring the aging process in stem cellsHematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress.Effects of dietary restriction on hematopoietic stem-cell aging are genetically regulated.Survival of irradiated recipient mice after transplantation of bone marrow from young, old and "early aging" miceCell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.Aging by epigenetics--a consequence of chromatin damage?Great promise of tissue-resident adult stem/progenitor cells in transplantation and cancer therapiesDNA repair is crucial for maintaining hematopoietic stem cell functionRecent progress on tissue-resident adult stem cell biology and their therapeutic implications.Targeting of cancer stem/progenitor cells plus stem cell-based therapies: the ultimate hope for treating and curing aggressive and recurrent cancers.FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cellsRecent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications.Klotho deficiency disrupts hematopoietic stem cell development and erythropoiesisStem cells, redox signaling, and stem cell aging.Chromatin: a molecular interface between cancer and aging.The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems.JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.The age of the target cell affects B-cell leukaemia malignancy.Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.Structural Features of the Telomerase RNA Gene in the Naked Mole Rat Heterocephalus glaber.Stem cells on patrol.Stem cell biology is population biology: differentiation of hematopoietic multipotent progenitors to common lymphoid and myeloid progenitorsLoss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitorsErythropoietin, GDF15, IL6, hepcidin and testosterone levels in a large cohort of elderly individuals with anaemia of known and unknown cause.Oxidized low-density lipoprotein induces hematopoietic stem cell senescence.Persistent injury-associated anemia and aging: Novel insights.
P2860
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P2860
Hematopoietic stem cell aging: mechanism and consequence.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Hematopoietic stem cell aging: mechanism and consequence.
@en
Hematopoietic stem cell aging: mechanism and consequence.
@nl
type
label
Hematopoietic stem cell aging: mechanism and consequence.
@en
Hematopoietic stem cell aging: mechanism and consequence.
@nl
prefLabel
Hematopoietic stem cell aging: mechanism and consequence.
@en
Hematopoietic stem cell aging: mechanism and consequence.
@nl
P2860
P1476
Hematopoietic stem cell aging: mechanism and consequence
@en
P2093
Derrick J Rossi
Irving L Weissman
P2860
P304
P356
10.1016/J.EXGER.2006.11.019
P50
P577
2007-01-31T00:00:00Z