Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines. - Wikidata - awgldk - TriplyDB

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

http://www.wikidata.org/entity/Q42824450

about

The emerging importance of group II PAKs Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration p21-activated kinase signaling in breast cancer Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer The role of p21-activated kinases in hepatocellular carcinoma metastasis Targeting Cdc42 in cancer PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?Signaling, Regulation, and Specificity of the Type II p21-activated Kinases Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3 Direct interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factor PAK4 kinase is essential for embryonic viability and for proper neuronal development Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor PAK thread from amoeba to mammals Protein kinase D regulates cofilin activity through p21-activated kinase 4 MicroRNA-433 inhibits cell proliferation in hepatocellular carcinoma by targeting p21 activated kinase (PAK4)p21-Activated kinase inhibitors: a patent review p21-Activated kinase 4 promotes prostate cancer progression through CREB p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells PAK6 targets to cell-cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape PAK as a therapeutic target in gastric cancer GL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling Pathways PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion.p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase Protein kinase D-mediated phosphorylation at Ser99 regulates localization of p21-activated kinase 4 PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis Identification and characterization of PS-GAP as a novel regulator of caspase-activated PAK-2 Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion.Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane.Activated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling.

P2860

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P2860

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

http://www.wikidata.org/entity/Q42824450

description

2001 nî lūn-bûn

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

2001年论文

@zh

2001年论文

@zh-cn

name

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@en

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@nl

type

label

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@en

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@nl

prefLabel

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@en

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines.

@en

P2093

Bahija Jallal

http://www.w3.org/2001/XMLSchema#string

Brian Schryver

http://www.w3.org/2001/XMLSchema#string

David B Whyte

http://www.w3.org/2001/XMLSchema#string

Felix Clairvoyant

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James R Bischoff

http://www.w3.org/2001/XMLSchema#string

Marinella G Callow

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Shirley Zhu

http://www.w3.org/2001/XMLSchema#string

Tod Smeal

http://www.w3.org/2001/XMLSchema#string

P2860

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

Oligomerization of DH domain is essential for Dbl-induced transformation

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

Structure of Cdc42 bound to the GTPase binding domain of PAK

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

P304

550-558

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scholarly article

P356

10.1074/JBC.M105732200

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P407

P433

1

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P478

277

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P577

2001-10-19T00:00:00Z

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P698

11668177

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