Efficient cell transformation by the Tpr-Met oncoprotein is dependent upon tyrosine 489 in the carboxy-terminus.
about
Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphataseThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseOncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastomaEssential role of Gab1 for signaling by the c-Met receptor in vivoBiology of MET: a double life between normal tissue repair and tumor progressionCoupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responsesMet receptor tyrosine kinase signals through a cortactin-Gab1 scaffold complex, to mediate invadopodiaDefining SH2 domain and PTP specificity by screening combinatorial peptide libraries.Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44.Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.RhoA-mediated signaling up-regulates hepatocyte growth factor gene and protein expression in response to apoptotic cellsCbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversionReceptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinomaThe EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met+ Hepatocellular Carcinoma.Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.Role of met axis in head and neck cancer.Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET.Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
P2860
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P2860
Efficient cell transformation by the Tpr-Met oncoprotein is dependent upon tyrosine 489 in the carboxy-terminus.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Efficient cell transformation ...... e 489 in the carboxy-terminus.
@en
Efficient cell transformation ...... e 489 in the carboxy-terminus.
@nl
type
label
Efficient cell transformation ...... e 489 in the carboxy-terminus.
@en
Efficient cell transformation ...... e 489 in the carboxy-terminus.
@nl
prefLabel
Efficient cell transformation ...... e 489 in the carboxy-terminus.
@en
Efficient cell transformation ...... e 489 in the carboxy-terminus.
@nl
P2093
P1433
P1476
Efficient cell transformation ...... ne 489 in the carboxy-terminus
@en
P2093
P304
P407
P577
1995-01-01T00:00:00Z