Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways. - Wikidata - awgldk - TriplyDB

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

http://www.wikidata.org/entity/Q42834927

about

SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity Tomosyn interacts with the SUMO E3 ligase PIASγ.A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics.Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a SUMO E3 ligase that is SIM-dependent and SUMO-2/3-specific.SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress Silencing nuclear pore protein Tpr elicits a senescent-like phenotype in cancer cells p53 post-translational modification: deregulated in tumorigenesis Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification.The transcriptional cofactor MCAF1/ATF7IP is involved in histone gene expression and cellular senescence TP53 status and response to treatment in breast cancers FAT10 modifies p53 and upregulates its transcriptional activity.SUMOylation of DLX3 by SUMO1 promotes its transcriptional activity.SUMOhunt: Combining Spatial Staging between Lysine and SUMO with Random Forests to Predict SUMOylation.RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction.Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H.Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance The in vivo role of androgen receptor SUMOylation as revealed by androgen insensitivity syndrome and prostate cancer mutations targeting the proline/glycine residues of synergy control motifs.Oxidative stress response and Nrf2 signaling in aging.SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase Coping with stress: multiple ways to activate p53.Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation.PML, SUMOylation, and Senescence Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts.Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance.Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function.Pc2-mediated SUMOylation of WWOX is essential for its suppression of DU145 prostate tumorigenesis.KSHV latent protein LANA2 inhibits sumo2 modification of p53.SUMOylation of p53 mediates interferon activities SUMO and the robustness of cancer.The SUMOylation of zinc-fingers and homeoboxes 1 (ZHX1) by Ubc9 regulates its stability and transcriptional repression activity.SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia.Kaposi's sarcoma-associated herpesvirus lana2 protein interacts with the pocket proteins and inhibits their sumoylation.Modification of Drosophila p53 by SUMO modulates its transactivation and pro-apoptotic functions.Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes.SUMOylation of Rb enhances its binding with CDK2 and phosphorylation at early G1 phase.Simultaneous measurement of SUMOylation using SNAP/CLIP-tag-mediated translation at the single-molecule level.In Vivo Detection and Analysis of Rb Protein SUMOylation in Human Cells.Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway.The Role of Sumoylation in Senescence.

P2860

Q24328747-3CA1E844-35F0-47F1-B1C2-C902A74D71DF Q28118946-974D26F4-64A4-4DD0-8B79-BC929B3B6BDF Q31153788-56846A8A-0EE2-4CBB-A212-7CFE9F6B7FA9 Q33596988-AD079A1A-883D-43F7-B364-96525D7A5BE3 Q33648307-6576783D-9673-40D6-8718-59A1AD301F71 Q33800141-73E81CDA-D222-4895-AA12-18260E0947FA Q33979961-FD4CA534-E106-4C04-80DD-F78D91647943 Q34300569-73B09A5F-BB95-467A-B85D-FC14C854C422 Q34483769-6F0A2055-8268-456A-8C6C-0DDCC364447E Q34918305-9C2ADB63-C813-4C02-A88F-A4D9EC337F7A Q35043933-44F65F22-9EC0-49B0-B969-4C72D7442D10 Q35097418-888AE008-4CE8-4C1F-859F-950E16C40ADA Q35234133-6B3B8C63-792D-44BD-B6A3-27CEDAE304C8 Q35362103-ABB41B81-77CE-42DD-B8BC-B20FEC0CC515 Q35657354-4B2EFAE5-3008-4F92-84D6-6737C607EFE8 Q35913673-289A8A24-320E-49B4-9A50-D686F6C7A3CC Q35946259-52183B2B-5C95-483E-B579-4BB8E4DA383D Q36225738-1485800A-9EA3-42CC-8BAC-5A6232CBF9FE Q36236785-967187A1-DD3E-44C7-BAD8-46A0FEDBFEB9 Q36278928-3AF5DB5A-DE82-4CF7-9FE4-2E41FC0335E1 Q36745375-8AE03F63-A3EB-4E07-8E7B-F570E3141D47 Q36858606-EAED622D-EBBA-49C9-B086-7B5DB4FED6A2 Q36981640-6782CCCF-D3B6-48C9-97A0-3D368C01D3D4 Q37349403-0711A2E3-DADC-49BC-B70C-C2FF67387D11 Q37415135-FB8EBE15-A4E4-4A8C-AC01-5335E0DB8D9A Q38103250-F5DC82DF-E030-4543-876F-D18FC46B22B9 Q38817885-0539F54B-B2F5-4DAF-8FE9-36A80562B8FB Q38917974-C34B8823-FF82-4BAE-A081-41A3EC04B300 Q39106989-1DD95E8E-667F-4D36-8A6C-376491F97FD3 Q39108925-87281142-25E0-4A72-A025-FFE5670A195B Q39149819-67FE2D65-8BCA-48EF-AB78-078314C7285E Q39176491-DE27711F-64A5-4163-A924-E563A822D303 Q39210824-4FF1D3FD-5DDF-4B2E-9603-829F9CA7A86F Q40423291-B4CB3905-0406-47DF-871F-A516DC808F0D Q42086146-B408B0F3-A39D-4C54-8F3B-59DF33A23C9B Q42408048-742E556A-43AA-44CF-A5A8-B75253DE3D3C Q46343177-014C7908-6EEC-4FBF-BE45-CA720E6516F7 Q47384716-60A09B63-7867-48A6-9FC3-5FDD920ADAC3 Q48267805-39FF5972-EB7F-45C8-81FD-9F15B593D155 Q51137583-461B45DC-A7F7-4499-80DA-E56F44C67266

P2860

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

http://www.wikidata.org/entity/Q42834927

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@en

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@nl

type

label

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@en

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@nl

prefLabel

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@en

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@nl

P1433

Q42834927-61233A6C-0B24-47CC-8C2B-25DEC5AD6A64

P1476

Q42834927-A8863145-C718-4DBB-8B7D-74BFE93EBCA1

P2093

Q42834927-2BE59199-C49B-4AE7-8F3A-B6C9CA08560E

Q42834927-44164AB4-7EC2-4BC1-B213-77B4CF8AC641

Q42834927-962E9FD3-6181-4387-84F4-FEE0D497040C

Q42834927-A741CA80-531B-40E5-858B-925A70F9F978

Q42834927-C79E5278-A7DC-4346-B5B4-52C1EA0DE24D

Q42834927-DBC39E99-5815-4061-B027-ECCEA8DBACAD

Q42834927-E9A5B983-7AAD-4A57-A70E-2F3B95E3BF68

P2860

Q42834927-07797E96-9D04-41FF-B8C6-B784A03EE96E

Q42834927-079535AB-B2C0-4502-A445-1DBDC0A1EBA4

Q42834927-18320347-6C91-46AA-B05E-CEB9D024B8DC

Q42834927-1BB5DF82-4EE9-4AF1-92FC-52BB996D2B13

Q42834927-2785078C-887B-4CD5-9247-1A1EBC6D115A

Q42834927-3A059C6C-391D-4DF3-BC42-EA7376B82D90

Q42834927-3F4298AE-EC43-46A6-AC0D-1F3077473E7B

Q42834927-4DAB3AC8-9A0E-4463-9697-D7DD434C148C

Q42834927-58CF75FF-5DC7-4E4D-917B-261B962D3002

Q42834927-63D26B93-A502-4F8A-937F-A7AD20F3BC3F

P304

Q42834927-6FD23A60-B99C-4FE7-8881-E25FDA95224F

P31

Q42834927-00361E97-737A-4DD1-91B4-6C861132ED94

P356

Q42834927-8F7637A3-01BD-49D3-B5AF-CD9D3E212853

P407

Q42834927-78C91AA4-58EE-46AF-97E5-1BAA0E1FBD63

P433

Q42834927-B627F861-A733-45F0-9E13-7D0BD230F25A

P478

Q42834927-58DAC5B2-B9B1-4527-A512-1518942A885B

P577

Q42834927-4ADBCF52-BC29-4D7E-8599-49AA1B82AA25

P698

Q42834927-C4DEB981-283E-421B-B6D7-9AF5FFC6E037

P356

P1433

Journal of Biological Chemistry

P1476

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.

@en

P2093

David C H Yang

http://www.w3.org/2001/XMLSchema#string

Ephrem Tekle

http://www.w3.org/2001/XMLSchema#string

Guanghui Wang

http://www.w3.org/2001/XMLSchema#string

P Boon Chock

http://www.w3.org/2001/XMLSchema#string

Rasa Santockyte

http://www.w3.org/2001/XMLSchema#string

Rong-Fong Shen

http://www.w3.org/2001/XMLSchema#string

Tianwei Li

http://www.w3.org/2001/XMLSchema#string

P2860

SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1

SUMO-1 modification activates the transcriptional response of p53

Distinct in vivo dynamics of vertebrate SUMO paralogues

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis

Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest

P304

36221-36227

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M608236200

http://www.w3.org/2001/XMLSchema#string

P407

P433

47

http://www.w3.org/2001/XMLSchema#string

P478

281

http://www.w3.org/2001/XMLSchema#string

P577

2006-09-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17012228

http://www.w3.org/2001/XMLSchema#string