Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils.
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Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosisPhysical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domainIdentification of UNC119 as a novel activator of SRC-type tyrosine kinasesRole of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophilsThrombopoietin stimulates cortactin translocation to the cytoskeleton independently of tyrosine phosphorylationChronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.Advances in the immunobiology of eosinophils and their role in disease.The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophilsTherapeutic strategies for allergic diseases.Novel therapy for asthma.Controlling allergic inflammation by signaling regulation of eosinophils.Identification of pro-inflammatory cytokines associated with muscle invasive bladder cancer; the roles of IL-5, IL-20, and IL-28A.Genomic microarrays: arraying order in biological chaos?Interleukin-5: a novel target for asthma therapy.Regulation of eosinophil viability by cytokines.Human versus mouse eosinophils: "that which we call an eosinophil, by any other name would stain as red".Intracellular signal transduction in eosinophils and its clinical significance.The role of Syk kinase in ultraviolet-mediated skin damageBalanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.Biochemical assessment of intracellular signal transduction pathways in eosinophils: implications for pharmacotherapy.Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB-induced Bcl-xL for inhibition of apoptosis.Cytokine-regulated accumulation of eosinophils in inflammatory disease.Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis.Src homology 2 protein tyrosine phosphatase (SHPTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival.Disruption of fas receptor signaling by nitric oxide in eosinophils.Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation.Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progressionCytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammationMultiple roles of Lyn kinase in myeloid cell signaling and function.Regulation of spontaneous eosinophil apoptosis-a neglected area of importance.Microarray analysis of eosinophils reveals a number of candidate survival and apoptosis genes.Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice.CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN.Essential Mechanisms of Differential Activation of Eosinophils by IL-3 Compared to GM-CSF and IL-5.Chemoattractant-induced signaling via the Ras-ERK and PI3K-Akt networks, along with leukotriene C4 release, is dependent on the tyrosine kinase Lyn in IL-5- and IL-3-primed human blood eosinophils.Involvement of Syk protein tyrosine kinase in LPS-induced responses in macrophages.A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.The immunopharmacology of skin inflammation: the future is already here!Association of Lyn tyrosine kinase to the GM-CSF and IL-3 receptor common betac subunit and role of Src tyrosine kinases in DNA synthesis and anti-apoptosis.
P2860
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P2860
Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@en
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@nl
type
label
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@en
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@nl
prefLabel
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@en
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@nl
P2093
P2860
P356
P1476
Requirement of Lyn and Syk tyr ...... ytokines in human eosinophils.
@en
P2093
P2860
P304
P356
10.1084/JEM.183.4.1407
P407
P577
1996-04-01T00:00:00Z