Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint. - Wikidata - awgldk - TriplyDB

Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.

Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.

http://www.wikidata.org/entity/Q42971190

about

A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling Cell division: control of the chromosomal passenger complex in time and space The current view for the silencing of the spindle assembly checkpoint KNL1: bringing order to the kinetochore Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response Bub3-BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomes Nup132 modulates meiotic spindle attachment in fission yeast by regulating kinetochore assembly.Bub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae.Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint)Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores A Centromere-Signaling Network Underlies the Coordination among Mitotic Events Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1 Gene and miRNA expression profiles of mouse Lewis lung carcinoma LLC1 cells following single or fractionated dose irradiation.Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation.Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis.Optimization of the analogue-sensitive Cdc2/Cdk1 mutant by in vivo selection eliminates physiological limitations to its use in cell cycle analysis A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling Molecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancer A motif from Lys216 to Lys222 in human BUB3 protein is a nuclear localization signal and critical for BUB3 function in mitotic checkpoint.DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity.Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae.

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Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.

http://www.wikidata.org/entity/Q42971190

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年论文

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2012年论文

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name

Phosphodependent recruitment o ...... ntains the spindle checkpoint.

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Phosphodependent recruitment o ...... ntains the spindle checkpoint.

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type

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Phosphodependent recruitment o ...... ntains the spindle checkpoint.

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Phosphodependent recruitment o ...... ntains the spindle checkpoint.

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Phosphodependent recruitment o ...... ntains the spindle checkpoint.

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Phosphodependent recruitment o ...... ntains the spindle checkpoint.

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J.CUB.2012.03.051

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Current Biology

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Phosphodependent recruitment o ...... intains the spindle checkpoint

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Alicja M Sochaj

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Graham J Buttrick

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John C Meadows

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Lindsey A Shepperd

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Theresa C Lancaster

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P2860

Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

Molecular analysis of kinetochore architecture in fission yeast

A quantitative atlas of mitotic phosphorylation

Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores

The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site

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891-899

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10.1016/J.CUB.2012.03.051

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10

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22

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Juri Rappsilber

Kevin G Hardwick

Jonathan B Millar

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2012-04-19T00:00:00Z

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224810325

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22521786

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P921

Bub1-Bub3 complex localization to kinetochore

bub1-bub3 complex

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3780767

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