The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration. - Wikidata - awgldk - TriplyDB

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

http://www.wikidata.org/entity/Q43002035

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Growth control mechanisms in neuronal regeneration The necessary role of mTORC1 in central nervous system axon regeneration.A liaison between mTOR signaling, ribosome biogenesis and cancer GSK3β regulates AKT-induced central nervous system axon regeneration via an eIF2Bε-dependent, mTORC1-independent pathway.mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system.Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules.Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion.The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms.Sphingosine 1-phosphate receptor 1 is required for retinal ganglion cell survival after optic nerve trauma.Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss.Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons.Activation of the Akt/mTOR signaling pathway: A potential response to long-term neuronal loss in the hippocampus after sepsis.The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.Can injured adult CNS axons regenerate by recapitulating development?Akt regulates neurite growth by phosphorylation-dependent inhibition of radixin proteasomal degradation.Activation of p70S6 Kinase-1 in Mesenchymal Stem Cells Is Essential to Lung Tissue Repair.Functional Interactions Between /S6K, /Notch, and Regulators of Fertility and Germline Stem Cell Maintenance Coordination of Necessary and Permissive Signals by PTEN Inhibition for CNS Axon Regeneration Ribosomal protein S6 kinase 1 promotes the survival of photoreceptors in retinitis pigmentosa

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The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

http://www.wikidata.org/entity/Q43002035

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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name

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

@en

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

@nl

type

label

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

@en

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

@nl

prefLabel

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

@en

The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration.

@nl

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Nature Communications

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The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration

@en

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Feisi Liang

http://www.w3.org/2001/XMLSchema#string

Haoliang Huang

http://www.w3.org/2001/XMLSchema#string

Jaloliddin Nuriddinov

http://www.w3.org/2001/XMLSchema#string

Liu Yang

http://www.w3.org/2001/XMLSchema#string

Michael E Selzer

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Shaohua Li

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Xiuyin Teng

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S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

mTOR signaling in growth control and disease

Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

Glial inhibition of CNS axon regeneration

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

Upstream and downstream of mTOR

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

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10.1038/NCOMMS6416

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