Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
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Coupling between catalytic site and collective dynamics: a requirement for mechanochemical activity of enzymesPCDB: a database of protein conformational diversityMany local motions cooperate to produce the adenylate kinase conformational transitionA dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysisCoarse-grained description of protein internal dynamics: an optimal strategy for decomposing proteins in rigid subunitsRational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteinsConformational transitions of adenylate kinase: switching by crackingRevealing the properties of plant defensins through dynamicsThermophilic proteins: insight and perspective from in silico experimentsCooperativity in monomeric enzymes with single ligand-binding sitesRNA mimicry by the fap7 adenylate kinase in ribosome biogenesisMinimum free energy path of ligand-induced transition in adenylate kinaseChanges in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family membersStructure of RNA 3′-phosphate cyclase bound to substrate RNAA Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its FamilyStructure and biochemical characterization of an adenylate kinase originating from the psychrophilic organismMarinibacillus marinusConformational sampling, catalysis, and evolution of the bacterial phosphotriesteraseAllostery in the ferredoxin protein motif does not involve a conformational switchBinding thermodynamics of a glutamate transporter homologDivergent evolution of protein conformational dynamics in dihydrofolate reductase.Improving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed EvolutionA Structural Ensemble for the Enzyme Cyclophilin Reveals an Orchestrated Mode of Action at Atomic ResolutionA GTP:AMP phosphotransferase, Adk2p, in Saccharomyces cerevisiae. Role of the C terminus in protein folding/stabilization, thermal tolerance, and enzymatic activity.Enzyme dynamics from NMR spectroscopyRational protein design: developing next-generation biological therapeutics and nanobiotechnological toolsSeeing the process of histidine phosphorylation in human bisphosphoglycerate mutaseAt the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?The role of oligomerization and cooperative regulation in protein function: the case of tryptophan synthaseEffects of macromolecular crowding on protein conformational changesBinding leverage as a molecular basis for allosteric regulationInterconversion of functional motions between mesophilic and thermophilic adenylate kinasesThermal adaptation of conformational dynamics in ribonuclease HPerspective: Defining and quantifying the role of dynamics in enzyme catalysisA simple model of backbone flexibility improves modeling of side-chain conformational variabilityThe role of dynamic conformational ensembles in biomolecular recognitionConformational plasticity surrounding the active site of NADH oxidase from Thermus thermophilus.Energy landscape along an enzymatic reaction trajectory: hinges or cracks?An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis.Mining electron density for functionally relevant protein polysterism in crystal structures.SDM--a server for predicting effects of mutations on protein stability and malfunction.
P2860
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P2860
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@en
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@nl
type
label
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@en
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@nl
prefLabel
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@en
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@nl
P2093
P356
P1476
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair.
@en
P2093
Dorothee Kern
Elan Z Eisenmesser
Georgia Hadjipavlou
Magnus Wolf-Watz
P2888
P304
P356
10.1038/NSMB821
P577
2004-08-29T00:00:00Z