A comparative study of methylglyoxal metabolism in trypanosomatids.
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Ethyl Pyruvate Emerges as a Safe and Fast Acting Agent against Trypanosoma brucei by Targeting Pyruvate Kinase ActivityChemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosomeGenomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African TrypanosomeTrypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate SynthaseThe R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis.Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages.Pyrosequencing of Mytilus galloprovincialis cDNAs: tissue-specific expression patterns.Synthesis and evaluation of indatraline-based inhibitors for trypanothione reductaseSynthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis.Activation of benznidazole by trypanosomal type I nitroreductases results in glyoxal formationProbing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucoseHomoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei.The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei.Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1.Polyamine metabolism in Leishmania: from arginine to trypanothione.Methylglyoxal metabolism in trypanosomes and leishmania.Glyoxalase diversity in parasitic protists.Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei.Comparative Metabolism of Free-living Bodo saltans and Parasitic Trypanosomatids.Mitochondrial pyruvate carrier in Trypanosoma brucei.Transcriptome and Functional Genomics Reveal the Participation of Adenine Phosphoribosyltransferase in Trypanosoma cruzi Resistance to Benznidazole.Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activityAntitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase.Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania major.The N-myristoylome of Trypanosoma cruzi.Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.Characterization of Bathyarchaeota genomes assembled from metagenomes of biofilms residing in mesophilic and thermophilic biogas reactors.A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism
P2860
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P2860
A comparative study of methylglyoxal metabolism in trypanosomatids.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
A comparative study of methylglyoxal metabolism in trypanosomatids.
@en
A comparative study of methylglyoxal metabolism in trypanosomatids.
@nl
type
label
A comparative study of methylglyoxal metabolism in trypanosomatids.
@en
A comparative study of methylglyoxal metabolism in trypanosomatids.
@nl
prefLabel
A comparative study of methylglyoxal metabolism in trypanosomatids.
@en
A comparative study of methylglyoxal metabolism in trypanosomatids.
@nl
P2860
P1433
P1476
A comparative study of methylglyoxal metabolism in trypanosomatids.
@en
P2093
Neil Greig
Stephen Patterson
P2860
P304
P356
10.1111/J.1742-4658.2008.06788.X
P407
P577
2008-12-03T00:00:00Z