Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.
about
A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune DiseasesDistinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.Identifying potent, selective protein tyrosine phosphatase inhibitors from a library of Au(I) complexes.Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases.Covalent inhibition of the lymphoid tyrosine phosphatase.PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis.Target-specific control of lymphoid-specific protein tyrosine phosphatase (Lyp) activityThe essential roles of chemistry in high-throughput screening triageThiuram disulfides as pseudo-irreversible inhibitors of lymphoid tyrosine phosphatase.Substrate selection influences molecular recognition in a screen for lymphoid tyrosine phosphatase inhibitorsInhibition of the lymphoid tyrosine phosphatase: the effect of zinc(II) ions and chelating ligand fragments on enzymatic activity.Synthesis of new pyrazolyl-2, 4-thiazolidinediones as antibacterial and antifungal agents.Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development.Role of the C1858T polymorphism of protein tyrosine phosphatase non-receptor type 22 (PTPN22) in children and adolescents with type 1 diabetes.C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?A three-dimensional chemical phase pharmacophore mapping, QSAR modelling and electronic feature analysis of benzofuran salicylic acid derivatives as LYP inhibitors.
P2860
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P2860
Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.
description
2008 nî lūn-bûn
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2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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name
Discovery of a novel submicrom ...... specific tyrosine phosphatase.
@en
Discovery of a novel submicrom ...... specific tyrosine phosphatase.
@nl
type
label
Discovery of a novel submicrom ...... specific tyrosine phosphatase.
@en
Discovery of a novel submicrom ...... specific tyrosine phosphatase.
@nl
prefLabel
Discovery of a novel submicrom ...... specific tyrosine phosphatase.
@en
Discovery of a novel submicrom ...... specific tyrosine phosphatase.
@nl
P2093
P2860
P1476
Discovery of a novel submicrom ...... specific tyrosine phosphatase
@en
P2093
Alison Rinderspacher
Caty Chung
Deborah H Smith
Donald W Landry
Dusica Vidović
Effie Tzilianos
Gangli Gong
Shi-Xian Deng
Stephan Schürer
Udo Toebben
P2860
P304
P356
10.1016/J.BMCL.2008.03.079
P407
P577
2008-04-08T00:00:00Z