Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. - Wikidata - awgldk - TriplyDB

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

http://www.wikidata.org/entity/Q43179830

about

Genome engineering using the CRISPR-Cas9 system CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants Genome Editing and Its Applications in Model Organisms Genome-editing tools for stem cell biology Classification and evolution of type II CRISPR-Cas systems Off-target Effects in CRISPR/Cas9-mediated Genome Engineering A CRISPR method for genome engineering CRISPR-Cas9 System as a Versatile Tool for Genome Engineering in Human Cells CCR5 gene disruption via lentiviral vectors expressing Cas9 and single guided RNA renders cells resistant to HIV-1 infection Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering CRISPR-Cas systems for editing, regulating and targeting genomes DNA targeting specificity of RNA-guided Cas9 nucleases High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells CRISPR RNA-guided activation of endogenous human genes Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination.Prefrontal cortex and the dysconnectivity hypothesis of schizophrenia.Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys.Cut site selection by the two nuclease domains of the Cas9 RNA-guided endonuclease.Super-resolution imaging of a 2.5 kb non-repetitive DNA in situ in the nuclear genome using molecular beacon probes.Next-generation mammalian genetics toward organism-level systems biology CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels.A single blastocyst assay optimized for detecting CRISPR/Cas9 system-induced indel mutations in mice Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems CRISPR/Cas9-mediated gene knock-down in post-mitotic neurons.Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice.An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system.Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9.Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease.CRISPR-mediated direct mutation of cancer genes in the mouse liver TALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery.CRISPR/Cas9 for genome editing: progress, implications and challenges.A mouse geneticist's practical guide to CRISPR applications.Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells.

P2860

Q22122027-039F9851-5636-4CDE-89D1-46FE3A265205 Q22337358-3611619E-7D50-4DDD-8F1D-ABE890F85B78 Q26753206-65C2D3D8-4D0A-4B2C-AE01-5317CFF48729 Q26768269-997596CB-60D9-4632-A7C2-59690606E0C8 Q26772108-ADFB3C47-7960-42CE-80D8-3D5A07974716 Q26800186-7D17382E-2CC6-46EA-97AF-272755946E80 Q26850610-B4A31D1D-55B8-4CED-9F92-CEBA9BD80FC5 Q26859390-B55FE89E-9707-4206-BD65-42AA70274F7A Q27000786-F945FC09-06AB-44F4-8278-633E2D801BAC Q28076522-429D30A7-1D2B-4A7C-BDEF-7B80107866C5 Q28542878-8F57B883-94A4-4CA9-A6C3-B614C5149161 Q28771473-99F3FE2B-F02A-4950-9463-4D932C6DE968 Q29547524-FD36C4B3-C076-4792-BDA1-AC8B623DA180 Q29615781-53F9A923-5B14-42F9-A1EC-3FFE85307757 Q29615793-CDFE0D1A-13AD-4C3A-B2E6-75229A1FE97A Q29616045-913FEF13-691E-4335-B72A-151537E1B684 Q29617072-4231FD68-1090-413C-9EF9-8D7013ABFEE5 Q30569839-DF3CA2C5-6275-47C4-89D2-89272BAE07FE Q30908684-512167B0-1438-4183-A869-3AE2DEAF59E9 Q31812558-35B6B338-32E9-4131-808F-C4CA62D38E18 Q33625156-BD373507-9877-4664-930B-E2F983C1700A Q33676643-C42428C1-A025-4EE8-9B8D-D364AF7B6819 Q33694108-8841A607-68A3-4F47-8469-F1F3D85EC734 Q33765741-B0BBB0BC-6670-4FC2-AFF1-4F1C9027A45F Q33766701-83ADFCE8-4C4C-451A-B191-7F2B374B61B9 Q33886976-3BA75056-CA9F-4C73-93BD-CECF6D093505 Q33890087-351CF815-EC5D-4AD8-A3D5-4EB02D6D6B1B Q33914125-F7074066-E5DF-4DD1-81A5-F44AD828B108 Q33985544-627E7D6A-34B1-4214-BCF8-C8418B15818B Q34039072-3BA922E7-F38A-4FFA-BD9B-312C26A2CF1A Q34070995-BC712607-18AF-43D9-BC49-6F20655E93EB Q34076889-286EC5B8-C990-4CBC-AAA5-A032B77BA093 Q34208869-D886B8CE-3026-4034-B35B-B3F11156FE52 Q34266447-BCCCB74E-3D78-4DE1-BF5D-605AE23C22E1 Q34346894-742A8F8F-797F-45B3-B820-CA586A0F1DC9 Q34353586-65DB5BEB-B331-400E-996E-062822150B0D Q34394269-565E02FF-C827-4AC7-B93C-EAAFE8B022D4 Q34411191-97856C82-FF96-4AA5-8B10-D2F13BF6D6B5 Q34441174-DCCF9BBC-9B48-410F-8C58-41A8F5F4906C Q34452056-491EFF7C-EA2D-41C7-B811-68CEFF9CD807

P2860

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

http://www.wikidata.org/entity/Q43179830

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh-hant

name

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@en

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@nl

type

label

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@en

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@nl

prefLabel

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@en

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@nl

P1433

Q43179830-ED1AC16D-8BE6-4C17-AFC0-95A856E475F8

P1476

Q43179830-9489B200-D2E6-4BF9-9157-C47D7F391F7F

P2093

Q43179830-265E9A99-5996-4EC9-AAF7-388C5FDF2BC7

Q43179830-559396B3-09AA-40EA-8CEA-75E6B7362132

Q43179830-655DFC7C-5384-43E2-AF05-CAFEBAF420CE

Q43179830-80BCB345-637B-4B10-AE91-82F5A96A5F4F

Q43179830-83CF251F-52BA-478A-8EBA-63FEF1173C43

Q43179830-9FEB16E3-F2A7-47C1-B482-5476522ABEA4

Q43179830-A1BDC0FB-ED80-4AE1-BCF2-42ED5A7E51ED

Q43179830-B62E330B-6A33-475E-9FA4-CD0B4826C10F

Q43179830-B9740ACD-A667-4802-BF89-3909D4522E0D

P2860

Q43179830-08CD8BD3-2036-4B4C-A3A8-5F33DC485517

Q43179830-1DFBEFE7-D1C8-4748-BF8D-8D321C99E028

Q43179830-1E2E940D-58A9-4458-A2A3-41F6AD07C677

Q43179830-29311980-0D78-4975-83BE-316F8B016DD6

Q43179830-319D6BE4-EE51-4495-ADF5-31ED1CB4E90C

Q43179830-413B566A-BCB3-448C-9816-C17D3BE19235

Q43179830-47E38206-F8FA-4DD8-A900-4C277F69B5AA

Q43179830-75DF76B9-2629-4FCC-A668-ED4BD1846884

Q43179830-7C567ED7-0950-48AC-B8FD-3FBB04DF3116

Q43179830-B5740018-A354-4F26-A652-05659593B6DD

P2888

Q43179830-1C411F05-DE63-464A-943B-A66B83047B1E

P304

Q43179830-EF0A98E6-CBC4-44BE-85E4-361D94D224DB

P31

Q43179830-9DC4F733-E4D3-4E1C-BDED-BA9E58522447

P356

Q43179830-58D9DC46-5418-4A52-857B-AD816617AE8F

P433

Q43179830-7699AD90-1693-4F54-A886-4AB4BCD9AF11

P478

Q43179830-4825CEAA-5425-44D3-9555-1E94A5945408

P577

Q43179830-E3818DF3-47C7-40E5-8E5E-E749182F664A

P5875

Q43179830-509A2B36-5D67-4669-A717-2140449CACAA

P6179

Q43179830-A85BBCDE-CED0-4795-8FB1-544610E6035F

P698

Q43179830-CD10FD42-E2ED-470B-AC46-2FFDA7918BE1

P932

Q43179830-A2E6F34D-D6F1-4D81-986F-E562CB257FA6

P356

P1433

P1476

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

@en

P2093

Bin Shen

http://www.w3.org/2001/XMLSchema#string

Hongya Wu

http://www.w3.org/2001/XMLSchema#string

Jianying Wang

http://www.w3.org/2001/XMLSchema#string

Jun Zhang

http://www.w3.org/2001/XMLSchema#string

Ke Ma

http://www.w3.org/2001/XMLSchema#string

Pumin Zhang

http://www.w3.org/2001/XMLSchema#string

Xingxu Huang

http://www.w3.org/2001/XMLSchema#string

Xueguang Zhang

http://www.w3.org/2001/XMLSchema#string

Zheng Li

http://www.w3.org/2001/XMLSchema#string

P2860

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

RNA-guided human genome engineering via Cas9

CRISPR-based adaptive immune systems

Multiplex genome engineering using CRISPR/Cas systems

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Activity, specificity and structure of I-Bth0305I: a representative of a new homing endonuclease family

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

RNA-guided genetic silencing systems in bacteria and archaea

Evolution and classification of the CRISPR-Cas systems

Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems

P2888

P304

720-723

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/CR.2013.46

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P577

2013-04-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

236096974

http://www.w3.org/2001/XMLSchema#string

P6179

1038811201

http://www.w3.org/2001/XMLSchema#string

P698

23545779

http://www.w3.org/2001/XMLSchema#string

P932

3641603

http://www.w3.org/2001/XMLSchema#string