Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
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Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathiesGene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian modelsParkinson's disease: animal models and dopaminergic cell vulnerabilityResistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activationα-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activityIdentification of allele-specific RNAi effectors targeting genetic forms of Parkinson's diseaseNigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease.Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?Etiology of Parkinson's disease: Genetics and environment revisitedGenetics of parkinsonism.Transgenic animal models of neurodegeneration based on human genetic studies.Gene-environment interactions in Parkinson's disease: the importance of animal modeling.Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerizationTargeted Overexpression of α-Synuclein by rAAV2/1 Vectors Induces Progressive Nigrostriatal Degeneration and Increases Vulnerability to MPTP in MouseMitochondrial dysfunction in genetic animal models of Parkinson's diseaseα-Synuclein and nonhuman primate models of Parkinson's diseaseThe etiopathogenesis of Parkinson disease and suggestions for future research. Part II.Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse.Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.Oxidative stress in genetic mouse models of Parkinson's disease.α-Synuclein nonhuman primate models of Parkinson's disease.Synuclein activates microglia in a model of Parkinson's disease.Influence of different promoters on the expression pattern of mutated human alpha-synuclein in transgenic mice.Early and late molecular events in neurodegeneration and neuroprotection in Parkinson's disease MPTP model as assessed by cDNA microarray; the role of iron.The therapeutic potential of LRRK2 and alpha-synuclein in Parkinson's disease.Overexpression of Parkinson's disease-associated alpha-synucleinA53T by recombinant adeno-associated virus in mice does not increase the vulnerability of dopaminergic neurons to MPTP.In vivo models of alpha-synuclein transmission and propagation.MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation.
P2860
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P2860
Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@en
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@nl
type
label
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@en
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@nl
prefLabel
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@en
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@nl
P2093
P1476
Sensitivity to MPTP is not inc ...... pha-synuclein transgenic mice.
@en
P2093
P304
P356
10.1046/J.1471-4159.2001.00366.X
P407
P577
2001-05-01T00:00:00Z