Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.
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Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesionsHeat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator ProteinAkt isoforms in vascular diseaseRegulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3Regulation of transforming growth factor-beta signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated proteinTyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signalingMultiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase BMembrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.Intramolecular and intermolecular interactions of protein kinase B define its activation in vivoReciprocal negative regulation of PDK1 and ASK1 signaling by direct interaction and phosphorylation.Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation.Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effectsPDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1.Multiple implications of 3-phosphoinositide-dependent protein kinase 1 in human cancer.Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology.Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway.PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains.The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression.Proteomics: current techniques and potential applications to lung disease.Regulation of NHE3 by lysophosphatidic acid is mediated by phosphorylation of NHE3 by RSK2.3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis.Acute neuroprotective synergy of erythropoietin and insulin-like growth factor ISrc kinase-targeted anti-inflammatory activity of davallialactone from Inonotus xeranticus in lipopolysaccharide-activated RAW264.7 cells.Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expressionAnalysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulationArsenic alters vascular smooth muscle cell focal adhesion complexes leading to activation of FAK-src mediated pathways.Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.Acute regulation of PDK1 by a complex interplay of molecular switches.PDK1 disruptors and modulators: a patent review.Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosisIncreased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation.Downregulation of nitrogen permease regulator like-2 activates PDK1-AKT1 and contributes to the malignant growth of glioma cells.CD28 Costimulation: From Mechanism to Therapy.Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination.Selective disruption of insulin-like growth factor-1 (IGF-1) signaling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death.Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif.
P2860
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P2860
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Identification of tyrosine pho ...... in regulating kinase activity.
@en
Identification of tyrosine pho ...... in regulating kinase activity.
@nl
type
label
Identification of tyrosine pho ...... in regulating kinase activity.
@en
Identification of tyrosine pho ...... in regulating kinase activity.
@nl
prefLabel
Identification of tyrosine pho ...... in regulating kinase activity.
@en
Identification of tyrosine pho ...... in regulating kinase activity.
@nl
P2093
P2860
P356
P1476
Identification of tyrosine pho ...... in regulating kinase activity.
@en
P2093
P2860
P304
37459-37471
P356
10.1074/JBC.M105916200
P407
P50
P577
2001-07-31T00:00:00Z