Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells.
about
Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismProtein phosphatase 5 protects neurons against amyloid-beta toxicityMolecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's diseaseThe role of mTOR signaling in Alzheimer diseasep75NTR-dependent modulation of cellular handling of reactive oxygen speciesDiminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell deathDiabetes mellitus: channeling care through cellular discoveryA peptide that binds specifically to the β-amyloid of Alzheimer's disease: selection and assessment of anti-β-amyloid neurotoxic effects.Presenilins regulate the cellular level of the tumor suppressor PTEN.Genetic programming by the proteolytic fragments of the amyloid precursor protein: somewhere between confusion and clarity.Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB.The sirtuin inhibitor nicotinamide enhances neuronal cell survival during acute anoxic injury through AKT, BAD, PARP, and mitochondrial associated "anti-apoptotic" pathways.MicroRNA‑34a induces apoptosis in PC12 cells by reducing B‑cell lymphoma 2 and sirtuin‑1 expression.Driving cellular plasticity and survival through the signal transduction pathways of metabotropic glutamate receptors.Cell Life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide.Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitusErythropoietin: elucidating new cellular targets that broaden therapeutic strategiesMechanistic insights into diabetes mellitus and oxidative stress"Sly as a FOXO": new paths with Forkhead signaling in the brainErythropoietin and oxidative stress.Neuroglobin protects PC12 cells against beta-amyloid-induced cell injuryPTEN in brain tumors.Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: implications for synaptic dysfunction and neuronal damageTherapeutic promise and principles: metabotropic glutamate receptorsInsulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets.The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease.Dietary polyphenol-derived protection against neurotoxic β-amyloid protein: from molecular to clinical.Gene expression profile of amyloid beta protein-injected mouse model for Alzheimer disease.Amyloid-beta peptides induce cell proliferation and macrophage colony-stimulating factor expression via the PI3-kinase/Akt pathway in cultured Ra2 microglial cells.Neuroprotection by Cocktails of Dietary Antioxidants under Conditions of Nerve Growth Factor DeprivationGinkgo biloba leaf extract improves the cognitive abilities of rats with D-galactose induced dementia.Regional hippocampal differences in AKT survival signaling across the lifespan: implications for CA1 vulnerability with aging.Diabesity and Brain Energy Metabolism: The Case of Alzheimer's Disease.Genetic variant of AKT1 and AKTIP associated with late-onset depression in a Brazilian population.Regional Health and Function in the hippocampus: Evolutionary compromises for a critical brain region.High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease.Methyl 3,4-dihydroxybenzoate protects primary cortical neurons against Aβ₂₅₋₃₅-induced neurotoxicity through mitochondria pathway.Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.
P2860
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P2860
Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Effect of the Alzheimer amyloid fragment Abeta
@nl
Effect of the Alzheimer amyloi ...... se and survival of PC12 cells.
@en
type
label
Effect of the Alzheimer amyloid fragment Abeta
@nl
Effect of the Alzheimer amyloi ...... se and survival of PC12 cells.
@en
prefLabel
Effect of the Alzheimer amyloid fragment Abeta
@nl
Effect of the Alzheimer amyloi ...... se and survival of PC12 cells.
@en
P2093
P2860
P1476
Effect of the Alzheimer amyloi ...... se and survival of PC12 cells.
@en
P2093
R López-Valdaliso
P2860
P304
P356
10.1046/J.1471-4159.2001.00472.X
P407
P577
2001-09-01T00:00:00Z