Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
about
Targeting purine and pyrimidine metabolism in human apicomplexan parasitesLigand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase.Chemotherapeutic hope on the horizon for Plasmodium vivax malaria?Pyrimethamine and WR99210 exert opposing selection on dihydrofolate reductase from Plasmodium vivax.Selective killing of the human malaria parasite Plasmodium falciparum by a benzylthiazolium dye.Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy.Dihydrofolate reductase inhibitors: developments in antiparasitic chemotherapy.Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.Synthesis of novel dopamine derived multidirectional ligands from cyanuric chloride: structural and antimicrobial studies.Enhanced in vitro activity of dihydrofolate reductase and dihydropteroase synthase inhibitors in combination against Nocardia spp.Quantitative structure activity relationship study of 2,4,6-trisubstituted-s-triazine derivatives as antimalarial inhibitors of Plasmodium falciparum dihydrofolate reductase.Synthesis, characterization and evaluation of 1,3,5-triazine aminobenzoic acid derivatives for their antimicrobial activity.Synthesis and biological evaluation of biguanide and dihydrotriazine derivatives as potential inhibitors of dihydrofolate reductase of opportunistic microorganisms.Synthesis and Preliminary Biological Evaluation of 1,3,5-Triazine Amino Acid Derivatives to Study Their MAO Inhibitors.Importance of cytochromes in cyclization reactions: quantum chemical study on a model reaction of proguanil to cycloguanil.The search for new DHFR inhibitors: a review of patents, January 2001 – February 2005Synthesis and Studies on S-Triazine-Based Ligand and Its Metal Complexes
P2860
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P2860
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@en
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@nl
type
label
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@en
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@nl
prefLabel
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@en
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@nl
P2093
P356
P1476
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
@en
P2093
Canfield CJ
Jacobus DP
Kotecka BM
Rieckmann KH
Terpinski J
P304
P356
10.1021/JM010089Z
P407
P577
2001-11-01T00:00:00Z