Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop.
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A Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase FoldDynamics-Driven Allostery in Protein KinasesUncovering Aberrant Mutant PKA Function with Flow Cytometric FRETDifferential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.Development of a microplate-based, electrophoretic fluorescent protein kinase a assay: comparison with filter-binding and fluorescence polarization assay formats.A rapid method for generation of selective Sox-based chemosensors of Ser/Thr kinases using combinatorial peptide libraries.Protein kinase A phosphorylation activates Vpr-induced cell cycle arrest during human immunodeficiency virus type 1 infection.Dynamic architecture of a protein kinase.Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation.pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model.Lethal, hereditary mutants of phospholamban elude phosphorylation by protein kinase A.Allosteric cooperativity in protein kinase A.A helix scaffold for the assembly of active protein kinasesSolution NMR Spectroscopy for the Study of Enzyme Allostery.Allostery and binding cooperativity of the catalytic subunit of protein kinase A by NMR spectroscopy and molecular dynamics simulations.Deception in simplicity: hereditary phospholamban mutations in dilated cardiomyopathy.KinView: a visual comparative sequence analysis tool for integrated kinome research.Proteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart.Fluram-Kemptide-Lys8 Non-radioactive Assay for Protein Kinase A.PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome.Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer.Characterization of substrates that have a differential effect on Saccharomyces cerevisiae protein kinase A holoenzyme activation.Decreased interactions in protein kinase A-glucocorticoid receptor signaling in the hippocampus after selective removal of the basal forebrain cholinergic input.A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis.Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling.A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5'-diphosphate accumulation.Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase.Water-mediated conformational preselection mechanism in substrate binding cooperativity to protein kinase A.Genetics: Pinpointing a hotspot in adrenal Cushing syndrome.Effect of H89 on the meiotic resumption of pig oocytes.A QM/MM study of the phosphoryl transfer to the Kemptide substrate catalyzed by protein kinase A. The effect of the phosphorylation state of the protein on the mechanism.
P2860
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P2860
Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
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2002年學術文章
@zh-hant
name
Structural basis for peptide b ...... the peptide-positioning loop.
@en
Structural basis for peptide b ...... the peptide-positioning loop.
@nl
type
label
Structural basis for peptide b ...... the peptide-positioning loop.
@en
Structural basis for peptide b ...... the peptide-positioning loop.
@nl
prefLabel
Structural basis for peptide b ...... the peptide-positioning loop.
@en
Structural basis for peptide b ...... the peptide-positioning loop.
@nl
P2093
P2860
P356
P1476
Structural basis for peptide b ...... the peptide-positioning loop.
@en
P2093
Joseph A Adams
Michael J Moore
Susan S Taylor
P2860
P304
10613-10618
P356
10.1074/JBC.M210807200
P407
P577
2002-12-23T00:00:00Z