Thymocyte expression of cathepsin L is essential for NKT cell development.
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Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosisGlobosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cellsTranscription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytesThe adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cellsPromiscuous processing of human alphabeta-protryptases by cathepsins L, B, and CPrss16 is not required for T-cell development.Lipid antigens in immunity.Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.Expression of hurpin, a serine proteinase inhibitor, in normal and pathological skin: overexpression and redistribution in psoriasis and cutaneous carcinomas.Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases.Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage developmentImmunohistochemical expression of cathepsin L in atopic dermatitis and lichen planus.Pivotal role of cathepsin K in lung fibrosis.Innate self recognition by an invariant, rearranged T-cell receptor and its immune consequences.Critical role for invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells.Processing of human protryptase in mast cells involves cathepsins L, B, and C.A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells.The split personality of NKT cells in malignancy, autoimmune and allergic disordersNonobese diabetic mice express aspects of both type 1 and type 2 diabetes.Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammalsNormal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency.Parallels and distinctions between T and NKT cell development in the thymus.Genetic control of NKT cell numbers.The Third Way: Progress on pathways of antigen processing and presentation by CD1.The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.Recognition of lipid antigens by T cells.MTP regulated by an alternate promoter is essential for NKT cell development.Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids.Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets.Specialized roles for cysteine cathepsins in health and disease.Engineered nanomaterial-induced lysosomal membrane permeabilization and anti-cathepsin agents.Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms.Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis.Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources.Antiinflammatory and immunosuppressive activity of sialostatin L, a salivary cystatin from the tick Ixodes scapularis.Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin.Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells.Gene expression profiles during human CD4+ T cell differentiation.
P2860
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P2860
Thymocyte expression of cathepsin L is essential for NKT cell development.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Thymocyte expression of cathepsin L is essential for NKT cell development.
@en
Thymocyte expression of cathepsin L is essential for NKT cell development.
@nl
type
label
Thymocyte expression of cathepsin L is essential for NKT cell development.
@en
Thymocyte expression of cathepsin L is essential for NKT cell development.
@nl
prefLabel
Thymocyte expression of cathepsin L is essential for NKT cell development.
@en
Thymocyte expression of cathepsin L is essential for NKT cell development.
@nl
P2093
P356
P1433
P1476
Thymocyte expression of cathepsin L is essential for NKT cell development.
@en
P2093
Albert Bendelac
Alexander Y Rudensky
Courtney Beers
Kamel Benlagha
Karen Honey
Katherine Forbush
Luc Teyton
Monique J Kleijmeer
P304
P356
10.1038/NI844
P407
P577
2002-10-07T00:00:00Z