Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes.
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Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2)Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease inductionSmall G proteins in the cardiovascular system: physiological and pathological aspectsVisual stimulation activates ERK in synaptic and somatic compartments of rat cortical neurons with parallel kineticsSelenium and its supplementation in cardiovascular disease--what do we know?Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptomeCardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in miceEstrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1Acute regulation of translation initiation by gonadotropin-releasing hormone in the gonadotrope cell line LbetaT2ERβ selective agonist inhibits angiotensin-induced cardiovascular pathology in female miceMolecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscleEukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signalingRapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signalingCyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes.Electroacupuncture at PC6 (Neiguan) Improves Extracellular Signal-Regulated Kinase Signaling Pathways Through the Regulation of Neuroendocrine Cytokines in Myocardial Hypertrophic RatsThe lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling.Aerosol delivery of kinase-deficient Akt1 attenuates Clara cell injury induced by naphthalene in the lungs of dual luciferase miceTuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner.PTPN11-associated mutations in the heart: has LEOPARD changed Its RASpots?PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines.In vivo efficacy of the AKT inhibitor ARQ 092 in Noonan Syndrome with multiple lentigines-associated hypertrophic cardiomyopathy.Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndromeThe mTOR pathway in the control of protein synthesis.Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function.Estrogen inhibits cardiac hypertrophy: role of estrogen receptor-beta to inhibit calcineurin.MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.Quantitative Non-canonical Amino Acid Tagging (QuaNCAT) Proteomics Identifies Distinct Patterns of Protein Synthesis Rapidly Induced by Hypertrophic Agents in Cardiomyocytes, Revealing New Aspects of Metabolic Remodeling.Differentiation-induced post-transcriptional control of B7-H1 in human trophoblast cells.Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.Cardiac and neuroprotection regulated by α(1)-adrenergic receptor subtypesMolecular mechanisms of cardiomyocyte aging.Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53.New approaches to prevent LEOPARD syndrome-associated cardiac hypertrophy by specifically targeting Shp2-dependent signaling.The rapid activation of protein synthesis by growth hormone requires signaling through mTOR.Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.Regulation of protein synthesis by eIF4E phosphorylation in adult cardiocytes: the consequence of secondary structure in the 5'-untranslated region of mRNA.
P2860
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P2860
Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@en
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@nl
type
label
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@en
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@nl
prefLabel
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@en
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@nl
P1433
P1476
Ras/Erk signaling is essential ...... nists in adult cardiomyocytes.
@en
P2093
Lijun Wang
P304
P356
10.1161/01.RES.0000041029.97988.E9
P577
2002-11-01T00:00:00Z