Functional improvement of dystrophic muscle by myostatin blockade.
about
Quadrupling muscle mass in mice by targeting TGF-beta signaling pathwaysEffects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained malesMyostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesisLatent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2Regulation of muscle growth by multiple ligands signaling through activin type II receptors.Follistatin gene delivery enhances muscle growth and strength in nonhuman primatesMyostatin from the heart: local and systemic actions in cardiac failure and muscle wastingMyostatin regulates cardiomyocyte growth through modulation of Akt signalingGenetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failureDelivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy.Myostatin negatively regulates satellite cell activation and self-renewalRecent advances in innovative therapeutic approaches for Duchenne muscular dystrophy: from discovery to clinical trialsThe quasi-parallel lives of satellite cells and atrophying muscleAdvancements in stem cells treatment of skeletal muscle wastingPharmacology of manipulating lean body massPre-clinical drug tests in the mdx mouse as a model of dystrophinopathies: an overviewOverexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβDystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures.Inhibitory control over Ca(2+) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expressionAnti-inflammatory drugs for Duchenne muscular dystrophy: focus on skeletal muscle-releasing factorsConcise Review: Epigenetic Regulation of Myogenesis in Health and DiseaseEmerging drugs for sarcopenia: age-related muscle wastingA mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient miceGenetic analysis of the role of proteolysis in the activation of latent myostatinMechanisms limiting body growth in mammalsAkt deficiency attenuates muscle size and function but not the response to ActRIIB inhibitionPostnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant miceMuscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition.Potent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin α2 chain-deficient muscular dystrophy.Structural basis for potency differences between GDF8 and GDF11.Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis.Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm.Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.Redundancy of myostatin and growth/differentiation factor 11 functionFunctional substitution by TAT-utrophin in dystrophin-deficient mice.Systemic myostatin inhibition via liver-targeted gene transfer in normal and dystrophic miceMaking fast-twitch dystrophic muscles bigger protects them from contraction injury and attenuates the dystrophic pathology.Myostatin is upregulated following stress in an Erk-dependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model.Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor.
P2860
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P2860
Functional improvement of dystrophic muscle by myostatin blockade.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Functional improvement of dystrophic muscle by myostatin blockade.
@en
Functional improvement of dystrophic muscle by myostatin blockade.
@nl
type
label
Functional improvement of dystrophic muscle by myostatin blockade.
@en
Functional improvement of dystrophic muscle by myostatin blockade.
@nl
prefLabel
Functional improvement of dystrophic muscle by myostatin blockade.
@en
Functional improvement of dystrophic muscle by myostatin blockade.
@nl
P2093
P356
P1433
P1476
Functional improvement of dystrophic muscle by myostatin blockade
@en
P2093
Elisabeth R Barton
Linda D Morris
Lisa-Anne Whittemore
Rexford S Ahima
Sasha Bogdanovich
Tejvir S Khurana
P2888
P304
P356
10.1038/NATURE01154
P407
P50
P577
2002-11-01T00:00:00Z
P6179
1021809955