Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation.
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Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7Ubiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosisSprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulationMonoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signalingUbiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosisTransport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitinationThe deubiquitinating enzyme USP10 regulates the post-endocytic sorting of cystic fibrosis transmembrane conductance regulator in airway epithelial cellsSuppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signalingGrb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradationAngiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradationActivated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradationCell signaling by receptor tyrosine kinasesThe ubiquitin proteasome system in neuropathologyAtypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review seriesA tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulationAMSH is an endosome-associated ubiquitin isopeptidaseNeuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisStructural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasiaRegulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomesUbiquitin-binding domainsARAP1 association with CIN85 affects epidermal growth factor receptor endocytic traffickingCbl promotes clustering of endocytic adaptor proteins.Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pitsSuppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases.TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin.Cbl controls EGFR fate by regulating early endosome fusion.Salt-induced changes in the plasma membrane proteome of the halotolerant alga Dunaliella salina as revealed by blue native gel electrophoresis and nano-LC-MS/MS analysis.Role of the ubiquitin proteasome system in renal cell carcinoma.The ubiquitination code: a signalling problem.The UPS: a promising target for breast cancer treatment.Regulation of ErbB2 receptor status by the proteasomal DUB POH1.The ORF3 protein of hepatitis E virus delays degradation of activated growth factor receptors by interacting with CIN85 and blocking formation of the Cbl-CIN85 complex.Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalizedD-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis.Cancer models in Caenorhabditis elegans.The developing story of Sprouty and cancer.The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.
P2860
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P2860
Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@en
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@nl
type
label
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@en
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@nl
prefLabel
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@en
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@nl
P2093
P356
P1476
Endocytosis of receptor tyrosi ...... ation, not polyubiquitylation.
@en
P2093
Gyorgi Vereb
Janos Szollosi
Keren Shtiegman
Menachem Katz
Yaara Zwang
Yaron Mosesson
Yosef Yarden
P304
21323-21326
P356
10.1074/JBC.C300096200
P407
P577
2003-04-28T00:00:00Z